Results 121 to 130 of about 4,954,671 (387)
Acta Crystallographica Section E: Crystallographic Communications, 2019 The crystal structure of sodium rubidium hydrogen citrate, NaRbHC6H5O7 or [NaRb(C6H6O7)]n, has been solved and refined using laboratory powder X-ray diffraction data, and optimized using density functional techniques.
Andrew J. Cigler, James A. Kaduk
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans [PDF]
, 2018 Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate ...
Baldwin +19 more
core +1 more source
Disodium hydrogen citrate sesquihydrate, Na2HC6H5O7(H2O)1.5
Acta Crystallographica Section E: Crystallographic Communications, 2016 The crystal structure of disodium hydrogen citrate sesquihydrate, 2Na2+·C6H6O72−·1.5H2O, has been solved and refined using laboratory X-ray single-crystal diffraction data, and optimized using density functional techniques.
Alagappa Rammohan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Guest displacement in silicon clathrates [PDF]
, 2004 We study both theoretically and experimentally the structure of the doped silicon clathrate II NaxSi34. We find that contrary to published works, the sodium atoms do not retain the T-d symmetry inside the Si-28 cages and move about 1 A away from the ...
Blase, Xavier +8 more
core +3 more sources
Effects of NaHCO3 Acclimation on Rye (Secale Cereale) Growth Under Sodic-Alkaline Stress
Plants, 2019 Sodic-alkalinity is a serious limiting factor in agricultural productivity. This study was conducted to examine the contribution of acclimation to the adaptation of rye (Secale cereale) to sodic-alkalinity.
Liyun Liu, Hirofumi Saneoka
doaj +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
A room-temperature sodium–sulfur battery with high capacity and stable cycling performance
Nature Communications, 2018 High-temperature sodium–sulfur batteries operating at 300–350 °C have been commercially applied for large-scale energy storage and conversion. However, the safety concerns greatly inhibit their widespread adoption.
Xiaofu Xu +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source