Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Different sodium levels and electrolyte balances in pre-starter diets for broilers
An experiment with 400 one-day-old male chicks (Ross) was conducted to evaluate the effects of different Na levels (0.10, 0.22, 0.34 and 0.46%) and different cation/anion balances (Na+K-Cl) (100, 150, 200, 250 and 300 meq/kg) in pre-starter diets on ...
A Maiorka +4 more
doaj +1 more source
The effect of preoperative sodium-glucose cotransporter 2 inhibitors on the incidence of perioperative metabolic acidosis: A retrospective cohort study [PDF]
Yudai Iwasaki +6 more
openalex +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Background: The aim of our study was to investigate if total bilirubin (T-bil), amylase (Amy), and sodium (Na) in nasogastric (NG) aspirates can reflect gastrointestinal motility reliably. Materials and Methods: NG aspirates from all laparotomies lasting
Go Miyano +4 more
doaj +1 more source
Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study [PDF]
Background: Gamma-hydroxybutyric acid (GHB), well known as a party drug, especially in Europe, is also legally used (sodium oxybate, Xyrem (R)) to treat a rare sleep disorder, narcolepsy with cataplexy.
Hertegonne, Katrien +3 more
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dietary sodium intake and all-cause mortality in kidney stone patients: a retrospective cohort study
BackgroundThe long-term effects of dietary sodium intake on patients with kidney stones remain unclear; hence, this study aims to investigate the correlation between dietary sodium intake and all-cause mortality in patients with kidney stones.MethodsThis
Shuangning Liu +5 more
doaj +1 more source
Concentration of Са2+, K+, Nа+ and their ratio in the Organa genitalia scrotum bovina
The research results indicate the presence of different concentrations in the scrotum tissue of Са2+ – 5–10, K+ – 42–181, Nа+ – 112–278 mM and their ratio of Nа+:Са2+ – 14–37:1, K+:Са2+ – 8–20:1 and Nа+:K+ – 1–4:1.
H. V. Maksymjuk
doaj +1 more source
Muscle Cramping During a 161-km Ultramarathon: Comparison of Characteristics of Those With and Without Cramping [PDF]
Background: This work sought to identify characteristics differing between those with and without muscle cramping during a 161-km ultramarathon. Methods: In this observational study, race participants underwent body weight measurements before, during ...
Hoffman, Martin D. +1 more
core +2 more sources

