Results 81 to 90 of about 4,954,671 (387)

Implementing Silicon Nanoribbon Field-Effect Transistors as Arrays for Multiple Ion Detection

Biosensors, 2016
Ionic gradients play a crucial role in the physiology of the human body, ranging from metabolism in cells to muscle contractions or brain activities. To monitor these ions, inexpensive, label-free chemical sensing devices are needed.
Ralph L. Stoop, Mathias Wipf, Steffen Müller, Kristine Bedner, Iain A. Wright, Colin J. Martin, Edwin C. Constable, Axel Fanget, Christian Schönenberger, Michel Calame   +9 more
doaj   +1 more source

Sodium‐sodium exchange through the sodium pump: the roles of ATP and ADP. [PDF]

The Journal of Physiology, 1979
1. We have developed a procedure for preparing resealed red cell ghosts that contain ADP but very little ATP. 2. The procedure involves (i) lysis of the cells in a very large volume of lysing solution, (ii) resuspension of the ghosts in a small volume, (iii) the incorporation into the ghosts, before they are resealed, of the adenylate kinase inhibitor ...
J D Cavieres, I M Glynn
openaire   +3 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Impact of Sodium Layer variations on the performance of the E-ELT MCAO module

, 2014
Multi-Conjugate Adaptive Optics systems based on sodium Laser Guide Stars may exploit Natural Guide Stars to solve intrinsic limitations of artificial beacons (tip-tilt indetermination and anisoplanatism) and to mitigate the impact of the sodium layer ...
Arcidiacono, C., Diolaiti, E., Hickson, P., Holzlöhner, R., Lombini, M., Pfrommer, T., Schreiber, L.   +6 more
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Ab initio quality neural-network potential for sodium

, 2010
An interatomic potential for high-pressure high-temperature (HPHT) crystalline and liquid phases of sodium is created using a neural-network (NN) representation of the ab initio potential energy surface.
E. Shpil’rain, Hagai Eshet, Jörg Behler, K. Syassen, Michele Parrinello, Rustam Z. Khaliullin, Thomas D. Kühne   +6 more
core   +1 more source

Glutathione accelerates sodium channel inactivation in excised rat axonal membrane patches [PDF]

, 1992
The effects of glutathione were studied on the gating behaviour of sodium channels in membrane patches of rat axons. Depolarizing pulses from –120 to –40 mV elicited sodium currents of up to 500 pA, indicating the simultaneous activation of up to 250 ...
B Neumcke, B Nilius, EM Fenwick, J Patlak, JB Patlak, JP Ruppersberg, M Kohlhardt, M Kohlhardt, M. Strupp, N. Mitrović, P Jonas, P. Grafe, PM Vassilev, R Stämpfli, S. Quasthoff, W Stühmer   +15 more
core   +1 more source

Electrolytic Balance in Broiler Chicks During the First Week of Age [PDF]

Brazilian Journal of Poultry Science, 2002
Two experiments were carried out using 712 day-old chicks to evaluate the electrolytic balance (Na+K-Cl) in pre-starter (1-7 days) broiler diets. The feed, based on corn and soybean meal with 21.5 % protein and 2,900 kcal ME/kg, was offered ad libitum ...
SA Borges, A Maiorka, AC Laurentiz, AV Fischer da Silva, E Santin, J Ariki   +5 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source