Results 161 to 170 of about 75,606 (303)

Integrative Multi‐Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN‐2, a Covalent FGFR Inhibitor

Advanced Science, Volume 12, Issue 14, April 10, 2025.
Using integrative multi‐omics analyses, this study maps FIIN‐2's targets and signaling networks in liver cancer cells, and identifies covalent AMPKα1 binding as a novel autophagy‐activating mechanism. The findings resolve both on‐target FGFR inhibition and off‐target protein engagement, providing a molecular roadmap to refine covalent kinase inhibitors
Ying Fu, Dandan Zhu, Xiaojuan Chen, Lingzhi Qu, Ming Guo, Shuhong Zhang, Guangyu Xu, Zhuchu Chen, Maoyu Li, Yongheng Chen   +9 more
wiley   +1 more source

Quenching of Singlet Oxygen by Sodium Azide in Reversed Micellar Systems [PDF]

, 1979
Norio Miyoshi, Giiti Tomita
openalex   +1 more source

ACTIONS OF SODIUM AZIDE [PDF]

British Journal of Pharmacology and Chemotherapy, 1949
openaire   +4 more sources

Integrative Transcriptome‐Wide Association Study With Expression Quantitative Trait Loci Colocalization Identifies a Causal VAMP8 Variant for Nasopharyngeal Carcinoma Susceptibility

Advanced Science, Volume 12, Issue 11, March 20, 2025.
Integrating transcriptome‐wide association study, expression quantitative trait loci, and genome‐wide association study identifies rs1058588 at the vesicle‐associated membrane protein 8 (VAMP8) locus as a risk variant for nasopharyngeal carcinoma (NPC).
Yan Liang, Xiang‐Yu Xiong, Guo‐Wang Lin, Xiaomeng Bai, Fugui Li, Josephine Mun‐Yee Ko, Yun‐He Zhou, An‐Yi Xu, Shu‐Qiang Liu, Shuai He, Pan‐Pan Wei, Qiu‐Yan Chen, Lin‐Quan Tang, Vivien Ya‐Fan Wang, Hai‐Qiang Mai, Chun‐Ling Luo, Yanni Zeng, Maria Li Lung, Mingfang Ji, Jin‐Xin Bei   +19 more
wiley   +1 more source

Airborne metal nanoparticles released by azides detonation: determination and potential public exposure

Scientific Reports
Metal azides are highly energetic materials that release a large amount of gas upon detonation. They also release metal particles, generating an aerosol. The most common azide is sodium azide (NaN3), which is used nowadays in car airbags.
Tianyu Cen, Zheyu Zhang, Laura Torrent, Elisabeth Müller, Christian Ludwig, Andrea Testino   +5 more
doaj   +1 more source

Activation of guanylate cyclase by sodium azide in rat adipocytes [PDF]

, 1976
Jacqueline Levilliers, Jacques Pairault, Françoise Lecot, M H Laudat   +3 more
openalex   +1 more source

LINC01235 Promotes Clonal Evolution through DNA Replication Licensing‐Induced Chromosomal Instability in Breast Cancer

Advanced Science, Volume 12, Issue 14, April 10, 2025.
This study elucidates the mechanism underlying LINC01235 promotes clonal evolution and selection under treatment pressure by facilitating DNA replication licensing and CIN, leading to increased therapeutic resistance in HER2+ breast cancer. Targeting LINC01235‐related pathways with ATR inhibitors may be a viable strategy for clinical application ...
Qi Zhang, Xuliren Wang, Zhibo Shao, Yi Zhang, Liyi Zhang, Ming Chen, Xujie Zhou, Han Zhu, Yue Zhou, Xinya Lu, Pei Li, Weiru Chi, Lun Li, Zhi‐Ming Shao, Shenglin Huang, Jingyan Xue, Yayun Chi, Jiong Wu, Bingqiu Xiu   +18 more
wiley   +1 more source

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source

Synthesis of azido derivatives of mucobromic acid

Bulletin of the Chemical Society of Ethiopia, 2013
Mucobromic acid is a highly reactive multicentered molecule. It was converted to its corresponding but unstable diazido derivative by reaction with two equivalents of sodium azide.
N. Mbebe, W. Masamba, N. D. Jumbam
doaj  

Heat resistant polymers of oxidized styrylphosphine [PDF]

, 1980
A flame resistant, nontoxic polymer which may be used safely in confined locations where there is inadequate ventilation is prepared either by polymerizing compounds having the formula R-N=P(C6H5)2(C6H4)CH=CH2 where R is an organic moeity selected from ...
Paciorek, K. J. L.
core   +1 more source