Results 241 to 250 of about 164,723 (328)

The Azidofunctionalization of Alkenes

open access: yesChemistryEurope, EarlyView.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

Surface modification of UV Cured epoxy resins by click Chemistry

open access: yes, 2010
Abadie   +47 more
core   +1 more source

A Modular Solid Phase Synthesis Approach for Glycocalix[4]Arene Derivatives and Their Multivalent Presentation on Ultrasmall Gold Nanoparticles.

open access: yesChemistry – A European Journal, EarlyView.
In this study, we present a calix[4]arene building block suitable for modular solid‐phase polymer synthesis and the preparation of functional glycocalix[4]arene. This allows us to incorporate carbohydrate ligands and further functionalities, such as alkynes at a specific position at the upper or lower rim of the calix[4]arene as demonstrated for the ...
Alisa Kayser   +8 more
wiley   +1 more source

Design of Potent Mannose‐6‐Phosphate Derivatives as Ligands for CI‐M6P/IGF2R Using Fluorescence Polarization Assay

open access: yesChemistry – A European Journal, EarlyView.
We designed and synthesized novel mannose‐6‐phosphate (M6P) derivatives to enhance their binding affinity for the CI‐M6P/IGF2 receptor, which plays a key role in lysosomal targeting. Using a fluorescence polarization assay, we evaluated di‐, tri‐, and penta‐M6P peptides and modified M6P analogs.
Lucie Mrázková   +11 more
wiley   +1 more source

Controlling Topology of a Telomeric G‐quadruplex DNA With a Chemical Cross‐link

open access: yesChemistry – A European Journal, EarlyView.
Thermodynamically stable G‐quadruplex (G4) DNA: Chemical cross‐linking between distant nucleotides led to formation of G4‐DNA that is stable in the presence of complementary DNA. This methodology can be used to reliably form G4s within DNA fibers for subsequent structural studies of G4‐protein interactions.
Bruce Chilton   +4 more
wiley   +1 more source

N,N‐Bis(trifluoromethyl)aminoacetonitrile: A Versatile Building Block for the Introduction of the Bis(trifluoromethyl)amino Group

open access: yesChemistry – A European Journal, EarlyView.
N,N‐Bis(trifluoromethyl)aminoacetonitrile (CF3)2NCH2CN, which is readily accessible, is established as a versatile starting compound for the synthesis of various types of (CF3)2N‐containing building blocks, that is, N‐heterocycles, alkenes, and acid derivatives such as N,N‐bis(trifluoromethyl)glycine.
Kristina A. M. Maibom   +14 more
wiley   +1 more source

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