Results 261 to 270 of about 168,123 (344)

Visible Light‐Promoted Aerobic Oxidation of Boronic Acids and Esters Utilizing a Benzothioxanthene Imide as the Photocatalyst

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A photochemical aerobic oxidation protocol using a benzothioxanthene imide as the photocatalyst at a low catalyst loading (0.01 mol%) is developed for the oxidation of boronic acids and esters. Herein, a sustainable and eco‐friendly protocol is reported for the aerobic photochemical oxidation of boronic acids or esters, utilizing a dibenzothioxanthene ...
Stamatis K. Serviou   +6 more
wiley   +1 more source

Clitocybe squamulosa Polysaccharides Ameliorate Dextran Sulfate Sodium‐Induced Colitis by Regulating the PI3K/AKt/mTOR Pathway and the Intestinal Flora in Mice

open access: yesFood Frontiers, EarlyView.
The potential mechanisms of CSFP and CE in alleviating UC. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent inflammation and ulceration of the colon. This research investigated the protective effects of Clitocybe squamulosa fruiting body polysaccharide (CSFP) and purified polysaccharides named CE on ...
Shuting Hou   +13 more
wiley   +1 more source

Modulating Neurotoxic Effects of Prenatal Chlorpyrifos Exposure Through Probiotic and Vitamin D Gestational Supplementation: Unexpected Effects on Neurodevelopment and Sociability

open access: yesFood Frontiers, EarlyView.
This study investigates whether gestational probiotic and vitamin D supplementation can mitigate CPF effects in Wistar rats. While supplementation did not reverse CPF‐induced deficits, it induced notable neurodevelopmental changes in control animals, underscoring the need for further research on prenatal supplementation safety.
Mario Coca   +8 more
wiley   +1 more source

Standardization of Microwave Heating Process Parameters for Extraction of Galactooligosaccharides (GOS) From Ricebean Flour

open access: yesFuture Postharvest and Food, EarlyView.
Extraction of Galactooligosaccharides (GOS) from ricebean through microwave heating. ABSTRACT Ricebean (Vigna umbellata) is a versatile, nutritious crop cultivated in hilly regions, offering significant nutritional contents and serving as a vital livelihood source for the Himalayan population.
Bharat Bhushan, Rakesh Kumar Raigar
wiley   +1 more source

Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m6A‐YTHDF2‐dependent mechanism

open access: yesiMeta, EarlyView.
Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu   +17 more
wiley   +1 more source

Targeting the hypoxia‐inducible factor‐1 alpha‐exoVEGF axis in tumor‐associated macrophages overcomes Bacillus Calmette‐Guérin immunotherapy resistance

open access: yesInterdisciplinary Medicine, EarlyView.
Macrophages stimulated by BCG significantly enhanced endothelial cell proliferation, migration, and tube formation. Mechanistically, this pro‐angiogenic activity was reliant on activating NF‐αB or other signaling pathways, which induced the upregulation of HIF‐1α and VEGFA.
Yuyang Hou   +10 more
wiley   +1 more source

Azide Anion Interactions with Imidazole and 1-Methylimidazole in Dimethyl Sulfoxide. [PDF]

open access: yesJ Phys Chem B
Rana D   +4 more
europepmc   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston   +2 more
wiley   +1 more source

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