The study investigated the changes in heavy metals and polyaromatic hydrocarbon contents of an oil-polluted soil as a result of exposure to sodium azide and hydroxylamine hydrochloride.
Beckley IKHAJIAGBE +1 more
doaj +1 more source
Synthesis, Anticancer and Antibacterial Activity of Mannose-based bis-1,2,3-Triazole Derivatives
In the current work, aromatic amines and alkyl halides have been converted to the corresponding azides 2a‒d and 4a-d by the reaction with sodium nitrite and sodium azide respectively for amines and sodium azide for halides.
Lamyaa Salih Mahdi +2 more
doaj +1 more source
Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles
A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide–internal alkyne 1,3-dipolar cycloaddition domino sequence ...
Rajesh K. Arigela +3 more
doaj +1 more source
End-group functionalization of poly(2-oxazoline)s using methyl bromoacetate as initiator followed by direct amidation [PDF]
Poly(2-alkyl/aryl-2-oxazoline)s (PAOx) are an alluring class of polymers for many applications due to the broad chemical diversity that is accessible for these polymers by simply changing the initiator, terminating agent and the monomer(s) used in their ...
Arys, Koen +4 more
core +2 more sources
Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant - Implications for disease susceptibility to Creutzfeldt-Jakob disease [PDF]
The human PrP gene (PRNP) has two common alleles that encode either methionine or valine at codon 129. This polymorphism modulates disease susceptibility and phenotype of human transmissible spongiform encyphalopathies, but the molecular mechanism by ...
Abdessamad Tahiri-Alaoui +56 more
core +1 more source
Azides are very versatile precursors of organic synthesis functionalities such as amines, isocyanates, sulfonamides, triazoles, tetrazoles, triazolines, aziridines, amino acids and diazo compounds.
Jean-Pierre Hagenbuch
doaj +1 more source
Microwave assisted metal-free approach to access 1,2,3-triazoles through multicomponent synthesis
The work illustrates multicomponent reaction of aldehydes, nitroalkanes and sodium azide for the metal-free synthesis of N-unsubstituted-1,2,3-triazoles using anthranilic acid as an organocatalyst under microwave irradiation. This is the first ever green
Anirban Garg +2 more
doaj +1 more source
Huisgen-based conjugation of water-soluble porphyrins to deprotected sugars: Towards mild strategies for the labelling of glycans [PDF]
Fully deprotected alkynyl-functionalised mono- and oligosaccharides undergo CuAAC-based conjugation with water-soluble porphyrin azides in aqueous environments.
Boyle, Ross W. +4 more
core +1 more source
Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase. [PDF]
Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and ...
Cui, Xianshu +6 more
core +1 more source
Ceruloplasmin Interferes with the Assessment of Blood Lipid Hydroperoxide Content in Small Ruminants
Simple and inexpensive analytical methods for assessing redox balance in biological matrixes are widely used in animal and human diagnostics. Two of them, reactive oxygen metabolites (ROMs) and total oxidant status (TOS), evaluate the lipid hydroperoxide
Stefano Cecchini Gualandi, Raffaele Boni
doaj +1 more source

