Results 51 to 60 of about 164,723 (328)

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Revealing the Effects of Three Different Antimicrobial Agents on E. coli Biofilms by Using Soft-Probe Scanning Electrochemical Microscopy

open access: yesApplied Nano, 2023
This paper evaluated the use of soft-probe scanning electrochemical microscopy complementarily with confocal laser scanning microscopy to study the effects of different antimicrobial agents and treatments on E. coli DH5α biofilm. The antimicrobial agents
Sorour Darvishi, Hubert H. Girault
doaj   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee   +12 more
wiley   +1 more source

Mutagenic effectiveness and efficiency of sodium azide in rice varieties

open access: yesElectronic Journal of Plant Breeding, 2020
This study was taken up to assess the chlorophyll spectrum induced by Sodium Azide mutagen in two rice cultivars- BPT 2231 and CO 51. The mutagenic effectiveness and efficiency of Sodium Azide across the two genotypes were also observed.
G. Vinithashri, S. Manonmani, G. Anand, S. Meena, K. Bhuvaneswari and A. JohnJoel
doaj   +1 more source

6-(Tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as Novel Potent CK2 Inhibitors

open access: yesMolecules, 2022
In this work, we describe the design, synthesis, and structure-activity relationship of 6-(tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as inhibitors of Casein kinase 2 (CK2).
Grigoriy V. Urakov   +6 more
doaj   +1 more source

Effect of chloride on the chemical conversion of nitrate to nitrous oxide for δ15N analysis [PDF]

open access: yes, 2009
We investigate the influence of chloride concentration on the performance of the chemical reduction method for measurement of the nitrogen isotopic ratio (δ15N) in NO3− in natural waters (McIlvin and Altabet, 2005).
Altabet, Mark A.   +2 more
core   +1 more source

Sodium azide enhancement of interleukin-2 production [PDF]

open access: yesBlood, 1983
The production of large quantities of Interleukin-2 (IL-2) from normal human lymphocytes has been limited by the short production and release period, as well as its absorption by the responsive cell population. We report the utilization of sodium azide (NaN3, 0.01% final concentration) to allow continued production of IL-2 as long as 72–96 hr and ...
Salvatore Venuta   +5 more
openaire   +3 more sources

Highly Sensitive Electrochemical Biosensor Based on Hairy Particles with Controllable High Enzyme Loading and Activity

open access: yesAdvanced Functional Materials, EarlyView.
For the first time, a highly sensitive electrochemical biosensor based on SiO2‐based hairy particles with a grafted PDMAEMA polymer brush containing a quantifiable and large amount of immobilized Laccase is reported. The fabricated biosensor exhibits a sensitivity of 0.14 A·m⁻¹, a limit of detection (LOD) of 0.1 µm, and a detection range of 0.3–750 µm,
Pavel Milkin   +7 more
wiley   +1 more source

Continual reproduction of self-assembling oligotriazole peptide nanomaterials. [PDF]

open access: yes, 2017
Autocatalytic chemical reactions, whereby a molecule is able to catalyze its own formation from a set of precursors, mimic nature's ability to generate identical copies of relevant biomolecules, and are thought to have been crucial for the origin of life.
Brea, Roberto J, Devaraj, Neal K
core   +2 more sources

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li   +9 more
wiley   +1 more source

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