Results 71 to 80 of about 167,415 (343)

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

Poly[di-μ2-azido-μ3-pyrazine-2-carboxylato-cadmium(II)]

Acta Crystallographica Section E, 2009
The title compound, [Cd(C5H3N2O2)(N3)]n, has been prepared by the reaction of pyrazine-2-carboxylic acid, cadmium(II) nitrate and sodium azide. In the structure, the CdII atom is six-coordinated by two azide anions and three pyrazine-2-carboxylate ...
Hui-Min Jin, Pei-Fan Li, Cai-Yun Li
doaj   +1 more source

6-(Tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as Novel Potent CK2 Inhibitors

Molecules, 2022
In this work, we describe the design, synthesis, and structure-activity relationship of 6-(tetrazol-5-yl)-7-aminoazolo[1,5-a]pyrimidines as inhibitors of Casein kinase 2 (CK2).
Grigoriy V. Urakov, Konstantin V. Savateev, Svetlana K. Kotovskaya, Vladimir L. Rusinov, Alexandr A. Spasov, Denis A. Babkov, Elena V. Sokolova   +6 more
doaj   +1 more source

Specificity and Kinetics of Haloalkane Dehalogenase [PDF]

, 1996
Haloalkane dehalogenase converts halogenated alkanes to their corresponding alcohols. The active site is buried inside the protein and lined with hydrophobic residues. The reaction proceeds via a covalent substrate-enzyme complex.
Janssen, Dick B.,, Kingma, Jaap,, Schanstra, Joost P.,   +2 more
core   +5 more sources

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source

Compound oxidized styrylphosphine [PDF]

, 1979
A process is described for preparing flame resistant, nontoxic vinyl polymers which contain phosphazene groups and which do not emit any toxic or corrosive products when they are oxidatively degraded.
Paciorek, K. J. L.
core   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

Optimization of gamma radiation and sodium azide treatments for induced mutations in ginger (Zingiber officinale Roscoe) tissue culture [PDF]

Emirates Journal of Food and Agriculture
Ginger (Zingiber officinale Roscoe) is a versatile herb commonly used in cooking, food processing, medicine, and as an ingredient in various products. As an economically significant crop, ginger also has substantial export potential.
Natnichaphu Sukin, Laksamon Soithong, Chayanid Saisanguan, Choosak Jompuk, Peeranuch Jompuk   +4 more
doaj   +3 more sources

Heat resistant polymers of oxidized styrylphosphine [PDF]

, 1978
Homopolymers, copolymers and terpolymers of a styrene based monomer are prepared by polymerizing at least one oxidized styrylphosphine monomer or by polymerizing p-diphenylphosphinestyrene and then oxidizing the polymerized monomer with an organoazide ...
Paciorek, K. J. L.
core   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu, Cătălina Ionela Zamfir, Cornel Baltă, Hildegard Herman, Alina Ciceu, Maria Alexandra Duma, Mariana Ioniță, Roxana‐Cristina Popescu, Anca Hermenean   +8 more
wiley   +1 more source