Results 101 to 110 of about 2,084,616 (297)

Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance

, 2014
Aldosterone promotes electrogenic sodium reabsorption through the amiloride-sensitive epithelial sodium channel (ENaC). Here, we investigated the importance of ENaC and its positive regulator channel-activating protease 1 (CAP1/Prss8) in colon.
Charles, R.P., Perrier, R., Wang, Q., Wang, Qing, Sergi, C., Hummler, Edith, Hummler, E., Malsure, Sumedha, Malsure, S., Charles, Roch-Philippe, Perrier, Romain, Christensen, B.M., Rossier, Bernard C, Maillard, Marc, Christensen, Birgitte Mønster, Rossier, B.C., Maillard, M., Sergi, Chloe   +17 more
core   +1 more source

Antinociceptive Effects of Sodium Channel-Blocking Agents on Acute Pain in Mice

Journal of Pharmacological Sciences, 2004
The effects of various sodium channel blocking agents on acute thermal and mechanical nociception, as assessed using the plantar and tail pressure tests, respectively, were compared with the effects of morphine. The drugs used were mexiletine, lidocaine,
Akiko Sakaue, Motoko Honda, Mitsuo Tanabe, Hideki Ono   +3 more
doaj   +1 more source

FastNano Liquid: An Automated Platform for Small‐Angle X‐ray Scattering‐Based Materials Discovery

Advanced Engineering Materials, EarlyView.
We present FastNano Liquid, an automated small‐ and wide‐angle X‐ray scattering platform for the combined synthesis and characterization of (nano)materials. The platform is coupled to varied reactor workflows for both in situ studies of reaction kinetics and ex situ screening of synthesis conditions to support machine learning‐guided exploration ...
Pierre‐Baptiste Flandrin, Émeline Cournède, Jens Krarup, Michael Lesa, Foyzul Hasan, Amandine Séné, Arnaud Lahouati, David Benhaiem, Jérémie‐Luc Sanchez, Simon Delacroix, Thierry Gacoin, Fabienne Testard, Damien Faivre, David Carriere, Corinne Chevallard, Olivier Taché, Mark A. Levenstein   +16 more
wiley   +1 more source

Molecular cloning and analysis of zebrafish voltage-gated sodium channel beta subunit genes: implications for the evolution of electrical signaling in vertebrates

BMC Evolutionary Biology, 2007
Background Action potential generation in excitable cells such as myocytes and neurons critically depends on voltage-gated sodium channels. In mammals, sodium channels exist as macromolecular complexes that include a pore-forming alpha subunit and 1 or ...
Zhong Tao P, Watanabe Hiroshi, Chopra Sameer S, Roden Dan M   +3 more
doaj   +1 more source

Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice [PDF]

, 2010
Duchenne muscular dystrophy (DMD) is a severe striated muscle disease due to the absence of dystrophin. Dystrophin deficiency results in dysfunctional sodium channels and conduction abnormalities in hearts of mdx mice.
Albesa, Maxime, Ogrodnik, Jakob, Jakob Ogrodnik, Hugues Abriel, Maxime Albesa, Jean-Sébastien Rougier, Rougier, Jean-Sébastien, Abriel, Hugues   +7 more
core   +2 more sources

Enhancing Low‐Temperature Performance of Sodium‐Ion Batteries via Anion‐Solvent Interactions

Advanced Functional Materials, EarlyView.
DOL is introduced into electrolytes as a co‐solvent, increasing slat solubility, ion conductivity, and the de‐solvent process, and forming an anion‐rich solvent shell due to its high interaction with anion. With the above virtues, the batteries using this electrolyte exhibit excellent cycling stability at low temperatures. Abstract Sodium‐ion batteries
Cheng Zheng, Qian Yao, Yanan Sun, Hongyu Lv, Zhongchao Bai, Guoliang Zhang, Nana Wang, Jian Yang   +7 more
wiley   +1 more source

Zur Wirkung des Seeanemonen Toxins II (ATX-II) auf spannungsgesteuerte Natriumionenkanäle neuronaler Zellen und zu den dadurch erreichten Änderungen im Schmerzempfinden [PDF]

, 2013
ATX-II wurde ursprünglich aus dem Gift der Seeanemone Anemonia sulcata isoliert und ist als potenter Aktivator spannungsgesteuerter Natriumionenkanäle (Navs) bekannt, da es einen persistierenden Na+-Strom induziert.
Klinger, Alexandra Birgit
core   +1 more source

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus

Neurobiology of Disease, 2011
Mutations in the neuronal voltage-gated sodium channel genes SCN1A and SCN2A are associated with inherited epilepsies, including genetic epilepsy with febrile seizures plus (GEFS+) and Dravet syndrome (severe myoclonic epilepsy of infancy).
Nicole A. Hawkins, Melinda S. Martin, Wayne N. Frankel, Jennifer A. Kearney, Andrew Escayg   +4 more
doaj   +1 more source

Biomass Native Structure Into Functional Carbon‐Based Catalysts for Fenton‐Like Reactions

Advanced Functional Materials, EarlyView.
This study indicates that eight biomasses with 2D flaky and 1D acicular structures influence surface O types, morphology, defects, N doping, sp2 C, and Co nanoparticles loading in three series of carbon, N‐doped carbon, and cobalt/graphitic carbon. This work identifies how these structural factors impact catalytic pathways, enhancing selective electron
Wenjie Tian, Jingkai Lin, Zhihao Tian, Selusiwe Ncube, Huayang Zhang, Emiliano Cortés, Hongqi Sun, Shaobin Wang   +7 more
wiley   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

Advanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein, Tiago Carneiro Gomes, Eliza Ng, Simon Rondeau‐Gagné, Tricia Breen Carmichael   +4 more
wiley   +1 more source