Results 211 to 220 of about 644,536 (348)

Three in a row—how sodium ions cross the channel

, 2016
Werner Kühlbrandt
openalex   +2 more sources

Heteroaryl Sodium Channel Inhibitors [PDF]

ACS Medicinal Chemistry Letters, 2013
openaire   +2 more sources

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Ectopic sodium channel expression decreases excitability of Drosophila Kenyon cells. [PDF]

J Physiol
Greenin-Whitehead K, Rozenfeld E, Moreno-Sanchez A, Tan MW, Kullu K, Ausborn J, Parnas M, Lin AC.   +7 more
europepmc   +1 more source

Elucidating the Specificity and Binding Rate of a Subtype Selective Sodium Channel Inhibitor with Molecular Dynamcis Simulations [PDF]

, 2018
Ben Corry
openalex   +1 more source

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Learning molecular traits of human pain disease via voltage-gated sodium channel structure renormalization. [PDF]

Comput Struct Biotechnol J
Xenakis MN, Lampert A.
europepmc   +1 more source

pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive

Advanced Functional Materials, EarlyView.
This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy, Udit Ghosh, Ketan A. Ganar, Hans Ippel, Ingrid Dijkgraaf, Siddharth Deshpande   +5 more
wiley   +1 more source

Clinical Efficacy and Safety Profile of Suzetrigine: A Novel Non-opioid Analgesic Targeting NaV1.8 Sodium Channel. [PDF]

Cureus
Rejeev MM, Pavithran K, Palatty P.
europepmc   +1 more source

Molecular Mechanisms of pH Modulation of Cardiac Sodium Channels (Nav1.5)

, 2017
Bicong Li
openalex   +1 more source