Results 251 to 260 of about 644,536 (348)

Cardiac Electrophysiological Effects of the Sodium Channel-Blocking Antiepileptic Drugs Lamotrigine and Lacosamide. [PDF]

Pharmaceuticals (Basel)
Wolfes J, Achenbach P, Wegner FK, Rath B, Eckardt L, Frommeyer G, Ellermann C.   +6 more
europepmc   +1 more source

Insight into the Internal Structure of Biogenic, Synthetic and Geological Apatite by Electron Microscopy and X‐Ray Scattering

Advanced Functional Materials, EarlyView.
Apatite occurs in many forms in nature, e.g. in teeth and geological minerals. Internally, biological apatite contains nanocrystals that are also found in synthetically prepared calcium phosphate nanoparticles which are used in biomedicine, e.g. for gene and drug delivery and for bone regeneration. Abstract Calcium phosphate is the inorganic component (
Kathrin Kostka, Oleg Prymak, Kateryna Loza, Matthias Epple   +3 more
wiley   +1 more source

Voltage-Gated Sodium Channel, as an Ion Channel in Therapeutics: A Bibliometric Analysis of Global Trends (1984-2023). [PDF]

Malays J Med Sci
Mohd Noor MR, Jamaludin SYN, Senik MH, Abdul Aziz MY.   +3 more
europepmc   +1 more source

Solvent‐Free Bonding Mechanisms and Microstructure Engineering in Dry Electrode Technology for Lithium‐Ion Batteries

Advanced Functional Materials, EarlyView.
Dry electrode technology revolutionizes battery manufacturing by eliminating toxic solvents and energy‐intensive drying. This work details two promising techniques: dry spray deposition and polymer fibrillation. How their unique solvent‐free bonding mechanisms create uniform microstructures for thicker, denser electrodes, boosting energy density and ...
Yuhao Liang, Hao Long, Zimo Huang, Ting He, Xueming Chen, Meng Li, Hao Chen, Shanqing Zhang   +7 more
wiley   +1 more source

Novel Dual 5-HT₇ Antagonists and Sodium Channel Inhibitors as Potential Therapeutic Agents with Antidepressant and Anxiolytic Activities. [PDF]

Pharmaceuticals (Basel)
Czopek A, Koczurkiewicz-Adamczyk P, Wójcik-Pszczoła K, Kornas D, Sitko W, Bucki A, Sapa M, Kamiński K, Satała G, Duszyńska B, Bojarski AJ, Latacz G, Czopek J, Szpor J, Dryja P, Sałat K.   +15 more
europepmc   +1 more source

Sodium Channel Binding [PDF]

, 2020
openaire   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

Advanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby, Yulia Marom, Guocong Lin, Aleksandra Baron‐Wiechec, Amit Meller   +4 more
wiley   +1 more source

The local anesthetic, lidocaine, suppresses the growth of colon cancer SW480 cells by decreasing the voltage-gated sodium channel subunit Na_v1.5. [PDF]

Sci Rep
Haraguchi-Suzuki K, Suzuki T, Nakasone C, Kawabata-Iwakawa R, Saito S.   +4 more
europepmc   +1 more source

Microplastics from Wearable Bioelectronic Devices: Sources, Risks, and Sustainable Solutions

Advanced Functional Materials, EarlyView.
Bioelectronic devices (e.g., e‐skins) heavily rely on polymers that at the end of their life cycle will generate microplastics. For research, a holistic approach to viewing the full impact of such devices cannot be overlooked. The potential for devices as sources for microplastics is raised, with mitigation strategies surrounding polysaccharide and ...
Conor S. Boland
wiley   +1 more source