Results 181 to 190 of about 126,825 (312)

Synthesis of Pyrido[2,3‐d]Azolopyrimidinones: Design and Epidermal Growth Factor Receptor‐Targeted Molecular Docking Toward Novel Anticancer Leads

open access: yesChemistryOpen, EarlyView.
New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha   +6 more
wiley   +1 more source

Treatment of pediatric epilepsy

open access: yesPediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li   +8 more
wiley   +1 more source

Crosslinked Gelatin‐Polycaprolactone Scaffolds: Balancing Biocompatibility and Inflammatory Response for Tissue Engineering Applications

open access: yesPolymer Engineering &Science, EarlyView.
Crosslinked gelatin‐functionalized PCL scaffolds exhibited enhanced hydrophilicity, structural stability, and porous interactions. In vitro assays demonstrated improved osteoblast adhesion, viability, and proliferation without cytotoxicity, while in vivo evaluation showed no adverse inflammatory response, supporting their potential application in ...
Fernanda Ramírez‐Ruiz   +7 more
wiley   +1 more source

Evaluating the potential of RNA interference for control of striped cucumber beetle, Acalymma vittatum (Fabricius) (Coleoptera: Chrysomelidae)

open access: yesPest Management Science, EarlyView.
SCB has a robust RNAi response to injected dsRNA, but oral RNAi is less efficient. Nucleases do not appear to be responsible for the discrepancy, suggesting other factors are involved. Abstract BACKGROUND The striped cucumber beetle (SCB) is a serious pest of cucurbit crops, causing damage both by feeding on plants and by vectoring plant diseases ...
Emine Kaplanoglu   +2 more
wiley   +1 more source

Integrated mechanisms linking sodium-potassium imbalance to salt-sensitive hypertension. [PDF]

open access: yesPhysiol Rep
Siakabanze C   +8 more
europepmc   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

open access: yesPest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian   +6 more
wiley   +1 more source

A Review of Metal–Organic Framework (MOF) Based Active Food Packaging: Materials Selection, Cellulose Matrices Current Advances, Synthesis and Characterizations

open access: yesPackaging Technology and Science, EarlyView.
Active packaging offers an effective approach to extending food shelf life. This review summarizes the past decade of progress in metal‐organic framework (MOF)‐based active food packaging, highlighting material selection, characterization, challenges, and future prospects.
Belladini Lovely   +4 more
wiley   +1 more source

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