Results 41 to 50 of about 234,202 (303)

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Reduction of salt: will iodine intake remain adequate in The Netherlands?

, 2010
Salt is the main vehicle for iodine fortification in The Netherlands. A reduction in salt intake may reduce the supply of iodine. Our aim was to quantify the effect of salt reduction on the habitual iodine intake of the Dutch population and the risk of ...
Ocke, M.C., Veer, P., van 't, van 't Veer, P., Verkaik-Kloosterman, J.   +3 more
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Effect of different levels of dietary sodium from sodium chloride on gastrointestinal tract response, tibia mineralization, and footpad dermatitis incidence in young turkeys

, 2012
SUMMARY The objective of this study was to determine whether different levels of dietary Na from NaCl affect gut function, tibia mineralization, and footpad dermatitis incidence in young turkeys. Male B.U.T.
J. Jankowski, Z. Zduńczyk, K. Lichtorowicz, J. Juśkiewicz   +3 more
semanticscholar   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

The Effects of Sodium Chloride versus Sodium Bicarbonate at the Same Dietary Sodium Concentration on Efficacy of Dietary Phytase and a Carbohydrase-Protease Cocktail in Broilers

, 2021
A trial was conducted to determine the effect of phytase (PHY) or a carbohydrase/protease cocktail (CPX) on broilers fed diets with two different levels of chloride (0.28% or 0.43%) created by altering dietary salt (NaCl) and sodium bicarbonate (NaHCO3).
Brake, J., Argüelles-Ramos, Mireille
core   +1 more source

Calcineurin inhibitors block sodium-chloride cotransporter dephosphorylation in response to high potassium intake.

Kidney International, 2017
Dietary potassium intake is inversely related to blood pressure and mortality. Moreover, the sodium-chloride cotransporter (NCC) plays an important role in blood pressure regulation and urinary potassium excretion in response to potassium intake ...
W. Shoda, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Takayasu Mori, E. Sohara, T. Rai, S. Uchida   +7 more
semanticscholar   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Short communication. Low dietary sodium content affects the digestibility of nutrients and fattening performance in growing rabbits

, 2007
An experiment was conducted to study the effect of a reduction in dietary sodium content on performance and nutrient digestibility, in rabbits weaned at 25 days of age.
Chamorro, S., Carabaño, R., Chamorro Francisco, Susana, Carabaño, Rosa, Gómez-Conde, M. S., Blas, Carlos, Blas, J. C., Gómez-Conde, María Soledad   +7 more
core   +1 more source