Results 51 to 60 of about 126,825 (312)

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

Advanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim, Yeojin Kim, Sanjita Paudel, In Young Kang, Suyeon Kim, Jeesoo Kim, Sunmi Park, Seung‐Hoi Koo, Hyun Sung Kim, Dae Won Jun, Jinyoung Park, Hyunbeom Lee, Joonseok Lee   +12 more
wiley   +1 more source

Dietary Impact of Adding Potassium Chloride to Foods as a Sodium Reduction Technique [PDF]

Nutrients, 2016
Potassium chloride is a leading reformulation technology for reducing sodium in food products. As, globally, sodium intake exceeds guidelines, this technology is beneficial; however, its potential impact on potassium intake is unknown. Therefore, a modeling study was conducted using Dutch National Food Survey data to examine the dietary impact of ...
van Buren, Leo, Dötsch-Klerk, Mariska, Seewi, Gila, Newson, Rachel S.   +3 more
openaire   +2 more sources

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan, Demeyer, Daniël, Mertens, Birgit, Ulens, Michèle   +3 more
core   +2 more sources

A Wearable, Dual Closed‐loop Insulin Delivery System for Precision Diabetes Management

Advanced Materials, EarlyView.
A wearable dual closed‐loop drug delivery system for diabetes management is presented, featuring an adaptive, on‐body trained edge AI algorithm for precise insulin delivery, which enhances therapeutic accuracy from 92.10% to 98.82%. Abstract Effective blood glucose management is an increasing demand worldwide.
Xuecheng He, Wei Huang, Wensheng Lin, Binbin Cui, Xinyu Tian, Jing Bai, Dingyao Liu, Ivo Pang, Hao Huang, Shixian Lin, Jixiang Zhu, Jinqiang Wang, Shiming Zhang   +12 more
wiley   +1 more source

Maternal dietary sodium chloride levels affect the sex ratio in rat litters

Physiology & Behavior, 1986
Eighty-eight adult female rats were fed diets containing either 0.08, 0.12, 1, 3, or 4% NaCl for at least one week prior to breeding and throughout gestation. Within 24 hours of birth, all pups were sexed based on anogenital distance, and the number of males and females were recorded.
E, Bird, R J, Contreras
openaire   +2 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Short-Term Exposure of Laying Hens to High Dietary Sodium Chloride Levels

Poultry Science, 1987
Four replicate pens, each containing five individually caged hens received a corn-soy basal diet to which .4, 1, 2, 4, or 6% NaCl was added during two 21-day experiments. An additional bilevel treatment, approximating a reported commercial feed production problem, consisted of 6% NaCl for 7 days followed by .4% NaCl for the remaining 2 weeks.
B L, Damron, L S, Kelly
openaire   +2 more sources

Food‐Based Edible Wireless Sensing Device with Isotropic Electromagnetic Response for Gastrointestinal Monitoring

Advanced Materials Technologies, EarlyView.
A sensor is fabricated that reflects electromagnetic waves wirelessly using only edible materials. The substrate is made of edible materials such as sugar and starch, and the electrodes are made of gold. This sensor has isotropic electromagnetic wave characteristics in response to rotation.
Ryosuke Matsuda, Kentaro Tomita, Shion Miura, Michiyuki Satoh, Tetsuo Kan, Hiroaki Onoe   +5 more
wiley   +1 more source

High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity

Frontiers in Immunology, 2019
Excess salt intake could affect the immune system by shifting the immune cell balance toward a pro-inflammatory state. Since this shift of the immune balance is thought to be beneficial in anti-cancer immunity, we tested the impact of high salt diets on ...
Ralf Willebrand, Ibrahim Hamad, Lauren Van Zeebroeck, Máté Kiss, Máté Kiss, Kirsten Bruderek, Anneleen Geuzens, Dries Swinnen, Beatriz Fernandes Côrte-Real, Lajos Markó, Els Lebegge, Els Lebegge, Damya Laoui, Damya Laoui, Josephine Kemna, Josephine Kemna, Thomas Kammertoens, Thomas Kammertoens, Sven Brandau, Jo A. Van Ginderachter, Jo A. Van Ginderachter, Markus Kleinewietfeld   +21 more
doaj   +1 more source