Results 31 to 40 of about 11,670 (181)
Promising Prodiginins Biological Activities
Chemistry &Biodiversity, EarlyView.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
LeuT Conformational Sampling Utilizing Accelerated Molecular Dynamics and Principal Component Analysis [PDF]
, 2012 Monoamine transporters (MATs) function by coupling ion gradients to the transport of dopamine, norepinephrine, or serotonin. Despite their importance in regulating neurotransmission, the exact conformational mechanism by which MATs function remains ...
Gedeon, Patrick C. +3 more
core +1 more source
Chemistry – A European Journal, Accepted Article.The tripyrrole alkaloid prodigiosin and related members of this family are structurally diverse bacterial secondary metabolites. The privileged scaffold accounts for versatile biological activities, e.g., antimicrobial, antitumoral, and immunosuppressive.
T. Moritz Weber, Joerg Pietruszka
wiley +1 more source
The Use of LeuT as a Receptor Model for Antidepressant Development [PDF]
, 2010 Selective serotonin re-uptake inhibitors (SSRIs) have been considered to be promising drugs in psychiatric practice because of their selectivity to serotonin re-uptake transporter (SERT).
Rustanti, L. (Lina)
core
Molecular theranostics: principles, challenges and controversies
Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley +1 more source
Food: An Unrecognized Source of Loop Diuretic Resistance [PDF]
, 2004 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90131/1/phco.24.6.630.34736 ...
Bard, Robert L. +2 more
core +1 more source
ChemistryOpen, EarlyView.A method to detect perchlorate ions and certify safe drinking water by constructing a fluorescence‐based logic gate considering the binding of a hemicyanine dye with β‐CD is presented. Perchlorate ions (ClO4−) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium‐iodide ...
Anusha C. M. +4 more
wiley +1 more source
Genomics‐assisted breeding for designing salinity‐smart future crops
Plant Biotechnology Journal, EarlyView.This review explores fast‐forward genomics‐assisted breeding tools to fast‐track the designing of salinity‐smart crops. Integration of various breeding tools can enhance salinity tolerance, ensuring sustainable agriculture and global food security. Summary Climate change induces many abiotic stresses, including soil salinity, significantly challenging ...
Ali Raza +6 more
wiley +1 more source
Pharmacy Practice, 2007 Thiazide diuretics are effective antihypertensive medications shown to reduce the risk of cardiovascular events and stroke. Despite being the preferred choice for uncomplicated essential hypertension, thiazide diuretics continue to be underutilized ...
Greene RS +2 more
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Environment International, 2019 In support of the Endocrine Disruptor Screening Program (EDSP), the U.S.EPA's Office of Research and Development (ORD) is developing high-throughput screening (HTS) approaches to identify chemicals that alter target sites in the thyroid hormone (TH ...
Jun Wang +7 more
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