Results 31 to 40 of about 828 (154)
Chemical and Pharmaceutical Bulletin, 1972 For the purpose of elucidating the metabolic sites of sodium cyclamate (CHS-Na), the influences of neomycin and sulfaguanidine on the metabolism of CHS-Na were investigated in rabbits, rats, and mice. Neomycin and sulfaguanidine caused a conspicuous decrease in the urinary excretion of CHS-Na metabolites in rats and mice.
SUENAGA, AYAKA +2 more
+6 more sources
Gas Chromatography of Sodium Cyclamate (II)
Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1970 Gas chromatographic procedure for the determination of sodium cyclamate was studied. According to recent studies, it has been reported that sodium cyclamate reacts with nitrite and produces cyclohexanol, cyclohexanone and cyclohexene. The author's experiment showed that the major product of the reaction was cyclohexyl nitrite, together with some ...
KATO, Saburo +2 more
openaire +3 more sources
Nutrition Journal, 2020 Background Consumption of non-nutritive sweeteners (NNS) is becoming increasingly more frequent, particularly in the context of obesity prevention policies.
Carolina Venegas Hargous +4 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Trypanosoma cruzi carbonic anhydrase (TcCA) has recently emerged as an interesting target for the design of new compounds to treat Chagas disease. In this study we report the results of a structure-based virtual screening campaign to identify novel and ...
Manuel A. Llanos +10 more
doaj +1 more source
In Silico Taste–Toxicity Study of New Hypothetical Hetero-Abiraterone Derivatives
Iraqi Journal of Industrial Research, 2022 First Iraqi attempt to study drug used for prostate cancer treatment (Abiraterone) that hypothetically reacted with known chemicals classified as Anticancer drug: Tirapazamine (T) and 5-Fluorouracil (F), food additive and preservative: Butylated Hydroxy ...
Kafa Khalaf
doaj +1 more source
Characterisation and stability of co-amorphous systems containing olanzapine and sulphonic acids
Annals of Medicine, 2021 Introduction A large number of active pharmaceutical compounds currently under development are poorly water soluble, which can limit their bioavailability and results in formulation challenges [1].
Inês A. Santos +3 more
doaj +1 more source
The choice of intense sweetener in the composition of medicated chewing gum under development
Фармацевтичний журнал, 2019 Considering the simplicity and ease of use, in recent years, more and more attention deserves medicated chewing gum (MCG), which plays the role of oral drug delivery system.
Yu. S. Maslii +2 more
doaj +1 more source
Macromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.Chewable softgels are a patient‐preferred alternative to conventional oral forms, offering pleasant taste, fast onset, and suitability for children or patients with swallowing difficulties. However, they present relevant challenges in their formulation: the shell must balance chewability, machinability, and stability, while the fill must mask the ...
Almudena Naharros‐Molinero +3 more
wiley +1 more source
EFSA Journal, Volume 24, Issue 2, February 2026.Abstract The present opinion deals with the re‐evaluation of sucralose (E 955) as food additive and with the safety of a proposed extension of use in food category (FC) 7.2 ‘Fine bakery wares’. Based on the available data, no safety concerns arose for genotoxicity of sucralose (E 955) and its impurities and degradation products.
EFSA Panel on Food Additives and Flavourings (FAF) +36 more
wiley +1 more source
Excretion and Distribution of Radioactive S35-Cyclamate Sodium (Sucaryl Sodium) in Animals.
Experimental Biology and Medicine, 1951 Summary1. The excretion and distribution of S35-sucaryl in the tissues of the rat, dog, and rabbit were studied. 2. By means of cold isotope dilution and paperchromato-graphic methods, it was shown that in the rat at least 95% of the material was excreted unchanged. 3.
J D, TAYLOR, R K, RICHARDS, J C, DAVIN
openaire +2 more sources