Results 111 to 120 of about 1,301,332 (323)
Regulation of PVT‐CeA Circuit in Deoxynivalenol‐Induced Anorexia and Aversive‐Like Emotions
The study investigates Deoxynivalenol (DON) effects on feeding and emotions, focusing on the central amygdala (CeA). Acute DON exposure reduces food intake and alters behavior, linked to CeAGABA neuron activity and PVT‐CeA connectivity. Manipulating CeAGABA neurons and using SCN10A antagonist A‐803467 alleviate DON's effects, offering potential ...
Liu‐Nan Yang+4 more
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi+9 more
wiley +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet+9 more
wiley +1 more source
Background/Aims: Inborn deficiency of the N-acetylglutamate synthase (NAGS) impairs the urea cycle and causes neurotoxic hyperammonemia. Oral administration of N-carbamoylglutamate (NCG), a synthetic analog of N-acetylglutamate (NAG), successfully ...
Birgitta C. Burckhardt+1 more
doaj +1 more source
A theoretical study of the role of astrocyte activity in neuronal hyperexcitability using a new neuro-glial mass model [PDF]
The investigation of the neuronal environment allows us to better understand the activity of a cerebral region as a whole. The recent experimental evidences of the presence of transporters for glutamate and GABA in both neuronal and astrocyte compartments raise the question of the functional importance of the astrocytes in the regulation of the ...
arxiv
This study uses Caenorhabditis elegans to assess the activity of amphetamine‐type stimulants (ATS) and their analogs. The research highlights the roles of dopamine and serotonin pathways, distinguishes chiral forms of ATS, and identifies structure‐activity relationships. These findings provide a rapid and cost‐effective model for evaluating the effects
Yuanpeng Li+3 more
wiley +1 more source
Does a glycine sodium nitrite crystal exist? [PDF]
The glycine sodium nitrite crystal reported by Khandpekar and Pati in the paper entitled, Synthesis and characterisation of glycine sodium nitrite crystals having non linear optical behaviour, Opt Commun 285, 2012 288-293 is actually gamma-glycine. In addition, we show that glycine barium ammonium nitrate, glycine sodium zinc sulfate, glycine barium ...
arxiv
The specific requirement for sodium chloride for the active uptake of
Joann Stevenson
openalex +1 more source
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li+11 more
wiley +1 more source