Results 31 to 40 of about 149,737 (259)

Methodology for measuring the mass fraction of monosodium glutamate in meat matrices [PDF]

open access: yesBIO Web of Conferences
Over the past century, human lifestyles and eating habits have changed dramatically as people in developed countries resort to fast food, they are indiscriminate and get used to frequent snacking. Production of dietary dishes and increase in the range of
Knyazeva A.C.   +4 more
doaj   +1 more source

INFLUENCE OF EXO- AND ENDOGENOUS FACTORS ON THE MORPHOLOGICAL AND FUNCTIONAL STATE OF THE SPLEEN AS AN IMPORTANT MEDICAL AND SOCIAL PROBLEM OF THE HEALTH CARE SYSTEM

open access: yesПроблеми екології та медицини, 2023
Over the past century, since the rapid development of mankind as a civilization, the state of the environment and the conditions of everyday human existence have undergone significant changes.
O.V. Mamai, S.M. Bilash, R.M. Grinko
doaj   +1 more source

Sodium-Stimulated Transport of Glutamate in Escherichia coli [PDF]

open access: yesJournal of Bacteriology, 1969
Wild-type Escherichia coli B grew poorly on glutamate as the sole carbon source, except at very high concentrations of the amino acid. The addition of sodium ion markedly stimulated the growth. It had the same effect in a mutant of E.
L, Frank, I, Hopkins
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Glutamate Transporters in Hippocampal LTD/LTP: Not Just Prevention of Excitotoxicity

open access: yesFrontiers in Cellular Neuroscience, 2019
Glutamate uptake is a process mediated by sodium-dependent glutamate transporters, preventing glutamate spillover from the synapse. Typically, astrocytes express higher amounts of glutamate transporters, thus being responsible for most of the glutamate ...
Joana Gonçalves-Ribeiro   +7 more
doaj   +1 more source

Reduced Sulfation Enhanced Oxytosis and Ferroptosis in Mouse Hippocampal HT22 Cells

open access: yesBiomolecules, 2020
Sulfation is a common modification of extracellular glycans, tyrosine residues on proteins, and steroid hormones, and is important in a wide variety of signaling pathways.
Haruna Nagase   +4 more
doaj   +1 more source

Regenerative glutamate release in the hippocampus of Rett syndrome model mice. [PDF]

open access: yesPLoS ONE, 2018
Excess glutamate during intense neuronal activity is not instantly cleared and may accumulate in the extracellular space. This has various long-term consequences such as ectopic signaling, modulation of synaptic efficacy and excitotoxicity; the latter ...
Saju Balakrishnan, Sergej L Mironov
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Effect of Carbon, Nitrogen and Salt Sources on the Growth of Monascus purpureus in Quinoa (Chenopodium quinoa)-Based Culture Media

open access: yesBiology and Life Sciences Forum, 2022
Monascus purpureus is produced in Asia and used as a food dye and for medicinal purposes. In the present study, the radial growth of quinoa flour-based culture media was evaluated on the tenth day after cultivation with different sources of carbon ...
Evelyn Quispe-Rivera   +5 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

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