Synergistic effects of bioactive silica and fluoride in enamel protection and repair: an in vitro study. [PDF]
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Comparison of the effect of self-assembling peptide P<sub>11</sub>-4 on post-bleaching shade stability and microhardness with different bioactive remineralization agents. [PDF]
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Taste exposure during different developmental phases impacts aversion learning in adult rats. [PDF]
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Bleaching efficacy and enamel effects of tricalcium phosphate dentifrices containing charcoal or hydrogen peroxide. [PDF]
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Sodium saccharin can be more acceptable to rats than pure saccharin
Behavioural Processes, 2018The artificial sweetener saccharin is available in several forms, including pure saccharin (S) and saccharin sodium salt hydrate (SSSH). Acceptance and preference relative to 2% sucrose for these two forms was assessed using both older female and young male rats.
Kieron Rooney +2 more
exaly +3 more sources
The in vitro effects of saccharin were evaluated in a transformed rat-bladder epithelial cell line. AY-27 cells were seeded in a 35-mm tissue culture well and incubated for 24 hr with saccharin or other test compounds dissolved in the media. The cytotoxic effects of saccharin were dependent on the salt form tested.
Samuel Cohen, S M Cohen, E M Garland
exaly +3 more sources
The thermal energy analysis of sodium saccharin
Food and Cosmetics Toxicology, 1978Abstract Sodium saccharin has been found to elicit a positive response, equivalent to about 0·0001 mol of an N-nitroso compound in thermal energy analysis. All efforts to ascribe this response to an N-nitroso impurity have been unsuccessful. It is concluded that the weak TEA response observed is due to the decomposition of sodium saccharin itself.
I.S. Krull +5 more
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Toxicological studies with sodium cyclamate and saccharin
Food and Cosmetics Toxicology, 1968Abstract The effects of acute, subacute and chronic administration of sodium cyclamate, sodium saccharin or combinations of cyclamate and saccharin have been studied in mice, rats and dogs. The acute toxicity of the materials was shown to vary with the strain of animal and the fat content of the diet.
J.D. Taylor +3 more
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The inhibition of urease and proteases by sodium saccharin
Cancer Letters, 1982Sodium saccharin, at concentrations similar to those in the urine of rats fed 1-5% sodium saccharin in their diet, markedly inhibited urease, and 3 proteases in vitro and sodium ion did not appear to play a role in enzyme inhibition. These observations suggest that enzyme inhibition of any of a large number of enzymes may play a role in the ...
E, Lok, F, Iverson, D B, Clayson
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Study of sodium saccharin co-carcinogenicity in the rat
Food and Chemical Toxicology, 1994A co-carcinogenicity experiment was conducted with female Sprague-Dawley rats in which the effects of short-term sodium saccharin dosing and initiation with a direct-acting carcinogen were examined in the urinary bladder. All initiated animals were administered 0.5 mg N-methyl-N-nitrosourea (MNU) by instillation into the bladder at 8 wk of age.
R W, West +4 more
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