Results 141 to 150 of about 5,140 (170)
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Food and Chemical Toxicology, 1985
The literature indicates that sodium saccharin is non-reactive to DNA and inactive as a gene mutagen in vitro. At elevated dose levels it is capable of producing structural disturbances in eukaryotic chromosomes in vitro, and it shows intermittent activity as a very weak germ-cell and somatic-cell mutagen in vivo.
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The literature indicates that sodium saccharin is non-reactive to DNA and inactive as a gene mutagen in vitro. At elevated dose levels it is capable of producing structural disturbances in eukaryotic chromosomes in vitro, and it shows intermittent activity as a very weak germ-cell and somatic-cell mutagen in vivo.
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Effect of short-term administration of sodium saccharin on rhesus monkeys
Food and Chemical Toxicology, 1984Sodium saccharin (NaS) was incorporated into biscuits or the drinking-water and fed to rhesus monkeys at progressively increasing doses in order to determine the maximum dose that the monkeys would voluntarily consume and/or tolerate. Very little rejection of NaS-treated biscuits or drinking-water was observed. However, severe diarrhoea which precluded
G.P. Schoenig +2 more
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Journal of Biomolecular Structure and Dynamics, 2019
In the past few decades, extensive discussions have been on the impact of artificial sweeteners on the risk of cancer. The present study aimed to evaluate the interaction of saccharin (SA) and sodium saccharin (SSA) with the promoter of the human p53 gene.
Mahboubeh, Mansourian +4 more
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In the past few decades, extensive discussions have been on the impact of artificial sweeteners on the risk of cancer. The present study aimed to evaluate the interaction of saccharin (SA) and sodium saccharin (SSA) with the promoter of the human p53 gene.
Mahboubeh, Mansourian +4 more
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Assay of saccharin and sodium saccharin in animal feed
Journal of Chromatography A, 1982H S, Tan, P W, Pan
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Journal of Chromatography A, 1984
A reversed-phase high-performance liquid chromatographic procedure for the determination of o-toluenesulfonamide and p-toluenesulfonamide in saccharin and saccharin sodium is described. In a second step, polar byproducts of the synthesis and related polar substances are determined in a lower sensitivity range.
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A reversed-phase high-performance liquid chromatographic procedure for the determination of o-toluenesulfonamide and p-toluenesulfonamide in saccharin and saccharin sodium is described. In a second step, polar byproducts of the synthesis and related polar substances are determined in a lower sensitivity range.
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Human detectability thresholds for saccharin, sodium saccharin, and sodium chloride.
Journal of Comparative and Physiological Psychology, 1970openaire +2 more sources