Results 131 to 140 of about 5,140 (170)
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Sodium Cyclamate, Saccharin and Food Efficiency
Nature, 1969FOLLOWING experiments with 0.43 per cent sodium cyclamate in rat's food1 in which rats consuming cyclamate had a better food efficiency than the controls, I performed two further experiments using two basic rations; saccharin was introduced, and both sweetening agents were given in varying amounts to weanling Wistar strain albino rats of both sexes ...
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The effect of sodium saccharin in the diet on caecal microflora
Food and Cosmetics Toxicology, 1980Abstract Total aerobic and anaerobic microbial populations of the caecum were compared in male rats fed 0 or 7·5% sodium saccharin for 10 days. The weights of caecal tissue and caecal contents were higher in the saccharin-fed animals than in the controls.
R L, Anderson, J J, Kirkland
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Spectrophotometric determination of sodium cyclamate and saccharin sodium with Astrazone Pink FG
The Analyst, 1984[No abstract available]
Güven K.C. +3 more
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Thermal investigation on polymorphism in sodium saccharine
Journal of Thermal Analysis and Calorimetry, 2014The thermal behavior of sodium saccharin polymorphic forms was investigated using thermogravimetry and differential scanning calorimetry, while structural changes during the dehydration processes were monitored by X-ray powder diffraction. In solid state, sodium saccharine may exhibit three forms: anhydrate, 2/3 hydrate (triclinic), and 15/8 hydrate ...
Deyber Arley Vargas Medina +2 more
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Antimutagenesis in Yeast by Sodium Chloride, Potassium Chloride, and Sodium Saccharin
1990Aqueous salt solutions containing NaCl, KCl, MgCl2, Na2SO4, CaCl2, NH4Cl, or sodium saccharin are mutagenic in yeast when logarithmic growth of cells is interrupted by exposure to a 0.5-2.0 M salt solution. Stationary-phase cells are not mutated by this treatment.
K R, Parker, R C, von Borstel
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Alterations in the rat kidney associated with sodium saccharin feeding
Toxicology Letters, 1982Sodium saccharin has previously been demonstrated to induce hyperplasia and tumors of the urothelium of the rat urinary bladder. It was fed as 5% of the diet to male F344 rats for 2 years. In the present experiment, mild simple hyperplasia of the urinary bladder epithelium was again frequently observed, and a marked nodular and papillary hyperplasia of
G, Murasaki, R E, Greenfield, S M, Cohen
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Production of Urinary Bladder Carcinomas in Mice by Sodium Saccharin
Science, 1970Pellets weighing 20 to 24 milligrams and containing 20 percent sodium saccharin suspended in cholesterol were surgically implanted into the urinary bladder lumens of female Swiss mice (60 to 90 days old) under ether anesthesia. Incidences of mouse bladder carcinomas in animals exposed to these pellets were 47 and 52 percent as compared with incidences ...
G T, Bryan, E, Ertürk, O, Yoshida
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Effect of sodium saccharin on the neonatal rat bladder.
Scanning microscopy, 1996In a two-generation bioassay, high doses of dietary sodium saccharin (NaSac) produce bladder carcinoma in rats, whereas acid saccharin (HSac) does not effect the urothelium. NaSac and HSac administered as 5% of the diet to F0 Sprague-Dawley (SD) and F344 rats, continued through to the weaned male rats for ten additional weeks.
Cohen, Samuel M. +5 more
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A review and biological risk assessement of sodium saccharin
Regulatory Toxicology and Pharmacology, 1992Dietary sodium saccharin is associated with bladder tumors when fed at high levels to the male rat. Under these conditions urinary pH, sodium concentration, and volume are elevated and proliferative changes are present in the urothelium. Extensive epidemiological studies have shown that saccharin does not increase the risk of bladder cancer in humans ...
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Saccharin sodium as a potential sweetener for antidotal charcoal
American Journal of Health-System Pharmacy, 1977This study explored if saccharin sodium, as a sweetener in activated charcoal formulations, would be sufficiently available to provide sweetness while not severely reducing charcoal's adsorption capacity. In vitro tests showed that charcoal takes up 40wt% of saccharin at a 1 g/liter concentration of saccharin in the residual fluid; 29.3wt% at 0.1 g ...
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