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Environmental Toxicology and Pharmacology, 2015 In the present study, the effect of sodium selenite on lead induced toxicity was studied in Wistar rats. Sodium selenite and lead nitrate were administered orally for 28 days to streptozotocin induced diabetic and non-diabetic rats.
Suna Kalender +2 more
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Sodium selenite and vitamin E in preventing mercuric chloride induced renal toxicity in rats
Food and Chemical Toxicology, 2014 This study aims to investigate improving effects of sodium selenite and/or vitamin E on mercuric chloride-induced kidney impairments in rats. Wistar male rats were exposed either to sodium selenite (0.25 mg/kg day), vitamin E (100 mg/kg day), sodium ...
Ayse Aslantürk +2 more
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Combined effect of sodium selenite and docetaxel on PC3 metastatic prostate cancer cell line
Biochemical and Biophysical Research Communications, 2011 Docetaxel and sodium selenite are well known for their anticancer properties. While resistance to docetaxel remains an obstacle in prostate cancer chemotherapy, sodium selenite, has been exploited as a new therapeutic approach.
Vera Alves +2 more
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Cardiac Effects of Sodium Selenite
Cardiology, 2008The classical idea that selenium is toxic to the heart at levels higher than available in a balanced diet is not supported by experimental work. In mice, treatment with sodium selenite increased the LD<sub>50</sub> of ouabain and 2,4-dinitrophenol, and increased the tolerance to nitrogen inhalation. Although sodium selenite had no effect on
D M, Aviado +3 more
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Respiratory responses to sodium selenite
Toxicology and Applied Pharmacology, 1961Summary Intravenous sodium selenite produced respiratory stimulation, increased minute volume, and a decreased tidal volume which appear to result from reflexes originating in the thorax. “Epinephrine” release could explain the early elevation of oxygen consumption noted after selenite.
M A, HEINRICH, D M, MACCANON
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Sodium selenite and cancer related lymphedema: Biological and pharmacological effects
Journal of Trace Elements in Medicine and Biology, 2016 A significant percentage of cancer patients develop secondary lymphedema after surgery or radiotherapy. The preferred treatment of secondary lymphedema is complex physical therapy.
Dawzcynski, Horst +2 more
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Acute Toxicity of Sodium Selenite to Juvenile Walleye
Bulletin of Environmental Contamination and Toxicology, 1999Selenium is a trace element normally found in surface waters at concentrations of approximately 0.1-0.3 μg/L (Lemly 1985). At slightly elevated concentrations (1-5 μg/L), it can bioaccumulate in the aquatic food chain, becoming highly toxic to fish and wildlife (Lemly and Smith 1987). Sandholm et al. (1973) found that fish accumulate selenium primarily
R J, Mauk, M L, Brown
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Sodium Selenite as an Anticancer Agent
Anti-Cancer Agents in Medicinal Chemistry, 2017Selenium (Se) is a ubiquitous, albeit not uniformly distributed metalloid present in earth crust. Consequently, its human intake with food products, particularly grains and vegetables, is also very uneven, and in certain cases can result in a severe Se deficiency.
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The effect of sodium selenite on chondrocytes in monolayer culture
Arthritis & Rheumatism, 1986AbstractThe effect of sodium selenite on DNA and sulfated proteoglycan synthesis by cultured rabbit articular and growth plate chondrocytes was studied as an in vitro model for Kashin‐Beck disease. The selenium content of a defined medium (DMEM, fibroblast growth factor, insulin, and dexamethasone) was below the limit of detection by isotope dilution ...
X, Wei, G C, Wright, L, Sokoloff
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Some effects of sodium selenite on the cardiovascular system
Toxicology and Applied Pharmacology, 1960Abstract The intravenous administration of 2.0 mg/kg Se as sodium selenite decreased systemic blood pressure and peripheral resistance. Pulmonary arterial pressure and resistance increased promptly and remained elevated until terminus. An initial increase was followed by a depression of cardiac output.
M A, HEINRICH, D M, MACCANON
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