Results 51 to 60 of about 3,351,616 (311)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Soft Pneumatic Bending Actuator with Integrated Carbon Nanotube Displacement Sensor

Robotics, 2016
The excellent compliance and large range of motion of soft actuators controlled by fluid pressure has lead to strong interest in applying devices of this type for biomimetic and human-robot interaction applications. However, in contrast to soft actuators
Tim Giffney, Mengying Xie, Aaron Yong, Andrew Wong, Philippe Mousset, Andrew McDaid, Kean Aw   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Low-cost, data-efficient, on-device soft sensors for sewer flow monitoring—learning from adjacent water level sensors

Water Research X
Flow measurements are critical for sewer monitoring, but direct measurements with flow meters are often expensive due to high sensor costs and frequent sensor maintenance.
Ruozhou Lin, Wenchong Tian, Ruihong Qiu, Lihan Hu, Zhiguo Yuan   +4 more
doaj   +1 more source

Soft Body Belt-Type Touch Sensor With Impact Resistance: A Study of Dynamic Behavior

IEEE Access, 2021
We report the development of a novel soft body touch sensor capable of measuring contact force along its length. The sensor can be embedded in soft objects and on curved surfaces for smart furniture, interactive electronics, and general robotics ...
Sophia L. Liu, Haoyuan Cai, Chang Liu
doaj   +1 more source

Self-healing sensorized soft robots

Materials Today Electronics, 2022
The lifetime of soft robots is limited by their susceptibility to damage. Recent breakthroughs in healable soft robots have overcome this issue by manufacturing systems from self-healing polymers. However, to operate and recover autonomously, compatible sensors need to be embedded. We show that innovative healable soft sensors to measure strain, force,
Roels, Ellen, Terryn, Seppe, Brancart, Joost, Sahraeeazartamar, Fatemeh, Clemens, Frank, Van Assche, Guy, Vanderborght, Bram   +6 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Soft touchless sensors and touchless sensing for soft robots

Frontiers in Robotics and AI
Soft robots are characterized by their mechanical compliance, making them well-suited for various bio-inspired applications. However, the challenge of preserving their flexibility during deployment has necessitated using soft sensors which can enhance their mobility, energy efficiency, and spatial adaptability.
Sirithunge, Chapa, Wang, Huijiang, Iida, Fumiya   +2 more
openaire   +5 more sources