Results 31 to 40 of about 5,235,793 (361)

Nanofiber-hydrogel composite–mediated angiogenesis for soft tissue reconstruction

Science Translational Medicine, 2019
A biodegradable nanofiber-hydrogel composite material promotes angiogenesis for soft tissue reconstruction in rodent and rabbit models. Crafting a (re)constructive composite To be useful for soft tissue reconstruction, a biomaterial should be compatible ...
Xiaowei Li, Brian Cho, Russell Martin, Michelle Y. Seu, Chi Zhang, Zhengbing Zhou, J. Choi, Xuesong Jiang, Long Chen, Gurjot Walia, Jerry Yan, Megan Callanan, Huanhuan Liu, K. Colbert, Justin Morrissette-McAlmon, W. Grayson, Sashank K Reddy, J. Sacks, H. Mao   +18 more
semanticscholar   +1 more source

The prognostic value of C-X-C motif chemokine receptor 4 in patients with sporadic malignant peripheral nerve sheath tumors

Chinese Journal of Cancer, 2017
Background Recent studies indicate that C-X-C motif chemokine receptor 4 (CXCR4) and its ligand, C-X-C motif chemokine ligand 12 (CXCL12), stimulate expression of the cell cycle regulatory protein Cyclin D1 in neurofibromatosis 1-associated malignant ...
Chao Zhang, Fang-Yuan Chang, Wen-Ya Zhou, Ji-Long Yang   +3 more
doaj   +1 more source

LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance

Cell Death and Disease, 2021
The refractory of castration-resistant prostate cancer (CRPC) is mainly reflected in drug resistance. The current research on the resistance mechanism of CRPC is still in its infancy.
Boya Zhang, Mingpeng Zhang, Chunyi Shen, Guancong Liu, Fan Zhang, Jingyu Hou, Weitao Yao   +6 more
doaj   +1 more source

Extracellular matrix-based scaffolding technologies for periodontal and peri-implant soft tissue regeneration.

The Journal of Periodontology, 2019
The present article focuses on the properties and indications of scaffold-based extracellular matrix technologies as alternatives to autogenous soft tissue grafts for periodontal and peri-implant plastic surgical reconstruction.
L. Tavelli, M. McGuire, G. Zucchelli, G. Rasperini, S. Feinberg, Hom-lay Wang, W. Giannobile   +6 more
semanticscholar   +1 more source

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

LncRNAs regulates cell death in osteosarcoma

Scientific Reports
Despite improvements, prognosis in osteosarcoma patients remains poor, making it essential to identify additional and more robust therapeutic targets. Non-apoptotic receptor-mediated cell death (RCD), which plays a crucial role in the pathogenesis of OS,
Ping’an Zou, Zhiwei Tao, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen, Li Niu   +6 more
doaj   +1 more source

Effects of soft tissue augmentation procedures on peri‐implant health or disease: A systematic review and meta‐analysis

Clinical Oral Implants Research, 2018
OBJECTIVE To review the dental literature in terms of soft tissue augmentation procedures and their influence on peri-implant health or disease in partially and fully edentulous patients.
D. Thoma, N. Naenni, E. Figuero, C. Hämmerle, F. Schwarz, R. Jung, I. Sanz-Sánchez   +6 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs

Biology Open, 2018
In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs (IVDs) between the five sacral vertebrae during childhood, and
Raffaella Bonavita, Kathleen Vincent, Robert Pinelli, Chitra Lekha Dahia   +3 more
doaj   +1 more source