Results 41 to 50 of about 150,928 (204)

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

Biphenotypic Sinonasal Sarcoma-Case Report and Review of Clinicopathological Features and Diagnostic Modalities. [PDF]

, 2019
Background Biphenotypic sinonasal sarcoma is a recently described malignancy showing dual differentiation with both myogenic and neural elements. Due to its histologic similarities to other sinonasal malignancies, it is a diagnostic challenge.
Chitguppi, Chandala, Collura, Kaitlin, Curtis, Mark, Koszewski, Ian, Nyquist, Gurston G., Rabinowitz, Mindy R., Rosen, Marc   +6 more
core   +2 more sources

LncRNAs regulates cell death in osteosarcoma

Scientific Reports
Despite improvements, prognosis in osteosarcoma patients remains poor, making it essential to identify additional and more robust therapeutic targets. Non-apoptotic receptor-mediated cell death (RCD), which plays a crucial role in the pathogenesis of OS,
Ping’an Zou, Zhiwei Tao, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen, Li Niu   +6 more
doaj   +1 more source

Lymph node metastases, sentinel lymph node biopsy, and lymphadenectomy in soft tissue sarcoma — when and why?

Oncology in Clinical Practice
The spread of soft tissue sarcomas (STS) through the lymphatic system occurs rarely, mainly in epithelioid sarcoma, angiosarcoma, rhabdomyosarcoma, and clear cell sarcoma (CARE). STS subtypes differ in terms of biological behavior.
Ada Niezgoda, Anna M. Czarnecka, Paulina Chmiel, Maria Krotewicz, Mateusz Spałek, Tomasz Świtaj, Paweł Rogala, Piotr Rutkowski   +7 more
doaj   +1 more source

Don't cancel the surgery just yet! A case report of positive preoperative pregnancy test due to a soft tissue sarcoma production of ectopic beta human chorionic gonadotropin. [PDF]

, 2018
Soft tissue sarcomas are a rare group of mesenchymal malignancies which can range from low to high grade. These tumors have different clinical, radiographic, and histopathological characteristics. Beta human chorionic gonadotropin is a naturally secreted
Blank, Alan Todd, Jones, Kevin B, Khalighi, Mazdak, Randall, R Lor   +3 more
core  

Pediatric Soft Tissue Sarcomas [PDF]

Surgical Clinics of North America, 2008
Soft tissue sarcomas in children are rare. Approximately 850 to 900 children and adolescents are diagnosed each year with rhabdomyosarcoma (RMS) or a non-RMS soft tissue sarcoma (NRSTS). RMS is more common in children 14 years old and younger and NRSTS in adolescents and young adults.
David M, Loeb, Katherine, Thornton, Ori, Shokek   +2 more
openaire   +2 more sources

Immunotherapy in Soft-Tissue Sarcoma [PDF]

Current Oncology, 2020
Soft-tissue sarcoma (sts) is a rare mesenchymal malignancy that accounts for less than 1% of all adult tumours. Despite the successful advancement of localized therapies such as surgery and radiotherapy, these tumours can, for many, recur—often with metastatic disease.
Ayodele, O., Razak, A.R. Abdul
openaire   +2 more sources

Surgical treatment of retrosternal extraosseous Ewing Sarcoma in a 6-years old female: a clamshell approach with hemysternectomy and application of a non-crosslinked extracellular matrix [PDF]

, 2017
Background Ewing Sarcoma (ES) and Neuroblastoma (NB) belong to a family of tumours of primitive neuroectodermal origin (PNET) that occurs in both bone and soft tissue. Notwithstanding ES and NB are two distinct malignant tumours, sometimes there could be
Angotti, Rossella, Casini, Leonardo, CLERICO, Anna, Luzzi, Luca, Messina, Mario, Molinaro, Francesco, Paladini, Piero, Pellegrino, Chiara, SCHIAVETTI, Amalia, Varrasso, Giulia   +9 more
core   +3 more sources

Retroperitoneal soft tissue sarcoma [PDF]

Cancer, 2005
AbstractThe objective of the current study was to define the optimal treatment for patients with retroperitoneal soft tissue sarcomas (RPS). The authors conducted a review of the pertinent literature and found that the majority of patients had locally advanced RPS at the time of diagnosis.
William M, Mendenhall, Robert A, Zlotecki, Steven N, Hochwald, Alan W, Hemming, Stephen R, Grobmyer, William G, Cance   +5 more
openaire   +2 more sources

Immunotherapy in sarcoma

Nowotwory, 2020
The introduction of immunotherapy with checkpoint inhibitors into clinical practice has radically changed the treatment and prognosis of patients with cancer.
Hanna Koseła-Paterczyk
doaj   +1 more source