Results 41 to 50 of about 447,491 (216)

Research on imbalance machine learning methods for MR $$T_1$$ T 1 WI soft tissue sarcoma data

BMC Medical Imaging, 2022
Background Soft tissue sarcoma is a rare and highly heterogeneous tumor in clinical practice. Pathological grading of the soft tissue sarcoma is a key factor in patient prognosis and treatment planning while the clinical data of soft tissue sarcoma are ...
Xuanxuan Liu, Li Guo, Hexiang Wang, Jia Guo, Shifeng Yang, Lisha Duan   +5 more
doaj   +1 more source

UK guidelines for the management of soft tissue sarcomas

British Journal of Cancer
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location, means that developing evidence-based guidelines is complicated by the ...
Andrew J. Hayes, Ioanna Nixon, Dirk C. Strauss, Beatrice M Seddon, A. Desai, Charlotte Benson, Ian R. Judson, Adam Dangoor   +7 more
semanticscholar   +1 more source

Expression of IL4Rα and IL13Rα1 are associated with poor prognosis of soft-tissue sarcoma of the extremities, superficial trunk, and retroperitoneum

Diagnostic Pathology, 2021
Background IL4Rα and IL13Rα1 are constituents of the type II IL4 receptor. Recently, IL4Rα and IL13Rα1 were reported to have roles in cancer progression and suggested as potential prognostic markers.
Kyoung Min Kim, Usama Khamis Hussein, See-Hyoung Park, Young Jae Moon, Zhongkai Zhang, Asmaa Gamal Ahmed, Ae-Ri Ahn, Ho Sung Park, Jung Ryul Kim, Kyu Yun Jang   +9 more
doaj   +1 more source

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model

OncoTarget, 2016
A patient with high grade undifferentiated pleomorphic soft-tissue sarcoma from a striated muscle was grown orthotopically in the right biceps femoris muscle of mice to establish a patient-derived orthotopic xenograft (PDOX) model.
T. Murakami, Jonathan C. Delong, F. Eilber, Ming Zhao, Yong Zhang, N. Zhang, Arun S. Singh, T. Russell, S. Deng, J. Reynoso, Cuong Quan, Yukihiko Hiroshima, R. Matsuyama, T. Chishima, Kuniya Tanaka, M. Bouvet, S. Chawla, I. Endo, R. Hoffman   +18 more
semanticscholar   +1 more source

In Vivo Bioorthogonal Chemistry Enables Local Hydrogel and Systemic Pro-Drug To Treat Soft Tissue Sarcoma

ACS Central Science, 2016
The ability to activate drugs only at desired locations avoiding systemic immunosuppression and other dose limiting toxicities is highly desirable.
J. M. Mejía Oneto, I. Khan, Leah M. Seebald, M. Royzen   +3 more
semanticscholar   +1 more source

Prognostic implications of PD-L1 expression in patients with soft tissue sarcoma

BMC Cancer, 2016
The PD-1/PD-L1 axis plays a paramount role in the immune escape of tumor cells by negative regulation of T-cell functions. The aim of the present study was to characterize the PD-L1 expression pattern and its clinical implication in soft-tissue sarcomas (
Chan Kim, Eun Kyung Kim, Hun Jung, H. Chon, J. Han, K. Shin, Hyuk Hu, Kyung S. Kim, Y. Choi, Sunghoon Kim, Young Han Lee, J. Suh, J. Ahn, H. Chung, S. Noh, S. Rha, S. Kim, H. Kim   +17 more
semanticscholar   +1 more source

Review on Lymph Node Metastases, Sentinel Lymph Node Biopsy, and Lymphadenectomy in Sarcoma

Current Oncology
Soft tissue sarcomas (STS) originating from connective tissue rarely affect the lymph nodes. However, involvement of lymph nodes in STS is an important aspect of prognosis and treatment. Currently, there is no consensus on the diagnosis and management of
Paulina Chmiel, Maria Krotewicz, Anna Szumera-Ciećkiewicz, Ewa Bartnik, Anna M. Czarnecka, Piotr Rutkowski   +5 more
doaj   +1 more source

Detection of SS18-SSX1/2 fusion transcripts in circulating tumor cells of patients with synovial sarcoma

Diagnostic Pathology, 2019
A recent study on 15 patients with synovial sarcoma demonstrated very low prevalence of tumor-specific fusion transcripts in peripheral blood specimens.
Joanna Przybyl, Matt van de Rijn, Piotr Rutkowski   +2 more
doaj   +1 more source

Soft tissue sarcoma of the extremities: pending questions on surgery and radiotherapy

Radiation Oncology, 2016
Soft tissue sarcomas are uncommon tumours of mesenchymal origin, most commonly arising in the extremities. Treatment includes surgical resection in combination with radiotherapy. Resection margins are of paramount importance in surgical treatment of soft
Fien Hoefkens, Charlotte Dehandschutter, J. Somville, P. Meijnders, D. Van Gestel   +4 more
semanticscholar   +1 more source

Effect of Surgical Excision Combined with Brachytherapy Treatment on Sarcoma Surrounding Important Nerve and Blood Vessels

Zhongliu Fangzhi Yanjiu, 2019
Objective To analyze the efficacy and safety of surgical excision combined with brachytherapy treatment on sarcoma surrounding important nerve and blood vessels.
ZHANG Chao, WANG Guowen, HAN Xiuxin, TENG Sheng, MA Yulin, CHEN Zhongjie, SUN Wujun   +6 more
doaj   +1 more source