Results 111 to 120 of about 430,233 (296)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evaluating Software Architectures: Development Stability and Evolution
, 2003 We survey seminal work on software architecture evaluation methods. We then look at an emerging class of methods that explicates evaluating software architectures for stability and evolution. We define architectural stability and formulate the problem of
Rami Bahsoon +3 more
core
, 2013 Every long-term used software system ages. Even though intangible goods like software do not degenerate in the proper sense, each software system degenerates in relation to the everlasting changes of requirements, usage scenarios and environmental ...
Braubach, Lars +6 more
core +1 more source
Staying Young at the Edge: A Software Aging Perspective for Foundation Models as a Service
ComputersNowadays, the emergence of Foundation Models as a Service enables mobile users to access powerful capabilities such as inference and fine-tuning on demand and without incurring local computational overhead.
Benedetta Picano, Romano Fantacci
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Predicting the Perception of Aging Based on Optimism in the Elderly People
Sālmand, 2020 Objectives Changes in aging peiod can have profound effects on the life and mental health of the elderly people. Optimism and perception of aging are among the factors associated with the psychological wellbing of the elderly people.
Hiwa Saleh Manige +6 more
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Towards controlling software architecture erosion through runtime conformance monitoring
, 2014 The software architecture of a system is often used to guide and constrain its implementation. While the code structure of an initial implementation is likely to conform to its intended architecture, its dynamic properties cannot always be fully checked ...
de Silva, Lakshitha R.
core