Results 91 to 100 of about 430,233 (296)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Multifaceted role of Iroquois signaling in development and diseases
Molecules and Cells: The Iroquois (Iro/Irx) gene family encodes transcription factors that belong to the Three-Amino-Acid Loop Extension-class homeodomain group, distinguished by a conserved Iro-box domain.
Ravi Shankar Goutam +7 more
doaj +1 more source
Optimized Differential Evolution Algorithm for Software Testing
International Journal of Computational Intelligence Systems, 2018 Differential evolution (DE) algorithms for software testing usually exhibited limited performance and stability owing to possible premature-convergence-related aging during evolution processes.
Xiaodong Gou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
SWARE: An approach to support software aging and rejuvenation experiments
, 2017 The need for uninterrupted computing services demands for high system availability and reliability. Techniques and methods to estimate and analyze system dependability are essential to support software deployment and maintenance.
Paulo Romero Martins Maciel +7 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Multi-scale entropy: One metric of software aging
, 2013 The phenomena of service performance or availability degradation have been widely observed in the long running software systems, which is called 'software aging'.
Pengfei Chen +9 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Software Rejuvenation - Do IT & Telco Industries Use It?
, 2012 Software rejuvenation has been addressed in hundreds of papers since it was proposed in 1995 by Huang et al. The growing number of research papers shows the great importance of this topic.
J. LI +11 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source