Results 71 to 80 of about 4,092,318 (302)

Measuring Anti-aging Effects in Drosophila

open access: yesBio-Protocol
One of the major factors contributing to aging and age-related diseases is the well-understood decline in the function of adult stem cells. Quantifying the degree of aging in adult stem cells is essential for advancing anti-aging mechanisms and ...
Hyun-Jin Na, Joung-Sun Park
doaj   +1 more source

Aging embrittlement at high temperature of 9Cr3W3Co steel and its improvement method

open access: yesCailiao gongcheng, 2019
The main factor that results in aging embrittlement of 9Cr3W3Co steel was investigated through microstructure observation using scanning electron microscopy (SEM). The amount of each precipitates under equilibrium state in 9Cr3W3Co steel with different W
MA Long-teng, LIU Zheng-dong, BAI Yin
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A Framework for Integrating Virtualized PAC into Availability Model of a Digital Substation: An Exploratory Adaptation of Software Aging and Rejuvenation Model

open access: yesElectricity
Software aging and the corresponding need for system rejuvenation are well-established concepts in computer science. As virtualization technologies are increasingly adopted within electric power utility infrastructures, early investigation into Software ...
Rizwan Rafique Syed   +1 more
doaj   +1 more source

Investigating Software Aging in LLM-Generated Software Systems

open access: yes2025 IEEE 36th International Symposium on Software Reliability Engineering Workshops (ISSREW)
Automatically generated software, especially code produced by Large Language Models (LLMs), is increasingly adopted to accelerate development and reduce manual effort. However, little is known about the long-term reliability of such systems under sustained execution.
César Santos   +2 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Other title: Kansas State Advisory Council on Aging report for fiscal years--Other title: Kansas Advisory Council on Aging annual report

open access: yes, 1979
The reports were prepared with the assistance of the Kansas Department on Aging.; Created in 1977 by the Kansas Act on the Aging, the ACA is represents different geographical, social and ethnic groups, with at least half its members being 60 years of age
Kansas Advisory Council on Aging.
core  

An interpretable multimodal ensemble assessment framework for Alzheimer’s disease cognitive staging

open access: yesFrontiers in Neurology
ObjectivesAlzheimer’s disease (AD) is the most prevalent type of neuro-degenerative dementia. Artificial intelligence assisted clinical evaluation can improve diagnostic efficiency and facilitate timely intervention.MethodsAn interpretable Multimodal ...
Jiale Zhang   +6 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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