Results 51 to 60 of about 4,092,318 (302)
IEEE Access, 2019 Most companies and organizations rely nowadays on virtualized environments to host and run their applications. Some of these applications have stringent availability and security requirements.
Matheus Torquato +2 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Software Licensing in the Cloud Age
CoRR, 2014 Cloud computing represents a major shift in information systems architecture, combining both new deployment models and new business models. Rapid provisioning, elastic scaling, and metered usage are essential characteristics of cloud services, and they require cloud resources with these same characteristics.
openaire +2 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
MedCSS: a causal self-supervised approach for hierarchical feature consistency in 3D medical imaging
Frontiers in NeuroscienceMedical image analysis plays a crucial role in linking perceptual mechanisms with clinical diagnosis, yet conventional deep learning models often rely on statistical correlations rather than modeling the underlying generative structure, leading to ...
Jiang Han +5 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Analysis of Software Aging in a Web Server [PDF]
A number of recent studies have reported the phenomenon of “software aging”, characterized by progressive performance degradation and/or an increased occurrence rate of hang/crash failures of a software system due to the exhaustion of operating system ...
Liz, Lei +3 more
core
JMIR AgingBackgroundGlobally, various aging concepts (such as healthy aging, successful aging, and active aging) have emerged to promote the goal of “aging well” and have gained widespread attention in academia, policy, and practice to change the negative ...
Na Xiao +5 more
doaj +1 more source