Results 61 to 70 of about 4,092,318 (302)
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Aging is a process that should be celebrated every day
, 2012 Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Matura, Pamela K. +1 more
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Aging connection (Columbus, Ohio : Online)
, 2006 Monthly; Electronic coverage as of May 22, 2007: Mar. 2006-; Description based on Mar. 2006; title from Web page (viewed on May 22, 2007).; Harvested from the web on 5/22/07June 2006, Ohio Leads Nation in Senior Services Levy Revenue. Department of Aging
Ohio. Dept. of Aging
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Retrofitting enables sustainability, Industry 4.0 connectivity, and improved usability
Advances in Industrial and Manufacturing EngineeringRetrofitting is a sustainable approach to improving the capabilities and extending the life of aging machine tools. Reusing the mechanical construction and replacing only the control electronics and software is a viable option to upgrade an aging machine
Tero Kaarlela +3 more
doaj +1 more source
Aging of Black Women: Reflections Based on Listening to Their Protagonists [PDF]
Psicologia: Teoria e PesquisaStudying the older, black, and female population implies the need to understand their experiences, as aging is not a universally uniform process. This article aims to investigate the social representations constructed by older black women, residents of ...
Polliana Teixeira da Silva +1 more
doaj +4 more sources
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Other title: [Kansas Department on Aging Overview]
, 2009 application/pdf; "February 17, 2009."; Presentation before the Kansas Legislature, House Social Services Subcommittee on the Kansas Department on Aging, by Secretary Kathy Greenlee, Kansas Department on Aging.Presentation discussing the Governor's budget
Greenlee, Kathy.
core +1 more source