Results 81 to 90 of about 2,127,647 (262)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Software defined airborne tactical network for aeronautic swarm
Tongxin xuebao, 2017 Aeronautic swarm was a new kind of aeronautic operationa1 system inspired by bio1ogica1 swarm behaviors.Whi1e 1eading to a new usage way of future aeronautic operationa1 resources，aeronautic swarm wou1d bring new cha11enges to the airborne tactica1 ...
Shang-hong ZHAO +4 more
doaj +2 more sources
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Crossfire Attack Defense Method Based on Software Defined Network [PDF]
Jisuanji gongchengUnlike conventional Distributed Denial of Service(DDoS) attacks, Crossfire attacks launched by botnets are low-speed and indistinguishable, making them difficult for traditional intrusion detection systems to defend against.
GUO Lei, JING Shan, WEI Liang, ZHAO Chuan
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Network security through software defined networking
Proceedings of the Conference on Principles, Systems and Applications of IP Telecommunications, 2014 Network security is a predominant topic both in academia and industry. Many methods and tools have been proposed but the attackers are still able to launch massive and effective attacks. Keeping the pace with the new threats appearing or becoming more sophisticated everyday is of a paramount of importance. Software Defined Networking (SDN) has recently
François, Jérôme +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Software Defined User Centric 5G Wireless Network Framework
Dianxin kexue, 2015 The radio access network of 5G is a complex heterogeneous network.The independence of different protocols limits the network performance. To unify the management of the heterogeneous network and provide personalized service，a software defined user ...
Hua Qu +4 more
doaj +2 more sources
Controller placement with critical switch aware in software-defined network (CPCSA). [PDF]
PeerJ Comput Sci, 2023 Muhammed Yusuf N +4 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source