Results 91 to 100 of about 6,721,355 (335)
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
Cleanroom software development [PDF]
The 'cleanroom' software development process is a technical and organizational approach to developing software with certifiable reliability. Key ideas behind the process are well structured software specifications, randomized testing methods and the ...
Dyer, M., Mills, H. D.
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FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
BioRel: towards large-scale biomedical relation extraction
BMC Bioinformatics, 2020 Background Although biomedical publications and literature are growing rapidly, there still lacks structured knowledge that can be easily processed by computer programs.
Rui Xing, Jie Luo, Tengwei Song
doaj +1 more source
Teaching Software Development to Non-Software Engineering Students [PDF]
This paper argues that although the object-oriented programming (OOP) paradigm is appropriate for students taking programming modules on Higher Education (HE) software engineering course, this paradigm is not as relevant for students from other courses ...
Colvin, John
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Software development: A paradigm for the future [PDF]
, 1989 A new paradigm for software development that treats software development as an experimental activity is presented. It provides built-in mechanisms for learning how to develop software better and reusing previous experience in the forms of knowledge ...
Basili, Victor R.
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FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Behavior Modeling on ARINC653 to Support the Temporal Verification of Conformed Application Design
IEEE Access, 2019 Numerous factors have an impact on the temporal correction of integrated modular avionics application. As early as in the design phase, verification should be conducted to guarantee the rigorous temporal requirements for safety consideration which are ...
Kui Zhang +4 more
doaj +1 more source
Automated software development workstation [PDF]
Engineering software development was automated using an expert system (rule-based) approach. The use of this technology offers benefits not available from current software development and maintenance methodologies.
core +1 more source
Value stream mapping for software development process [PDF]
, 2004 Includes bibliographical ...
Thummala, Ganesh S.
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