Results 71 to 80 of about 4,581,706 (333)

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

UN PATRÓN DE INTERACCIÓN ENTRE DIAGRAMAS DE ACTIVIDADES UML Y SISTEMAS WORKFLOW AN INTERACTION PATTERN BETWEEN UML ACTIVITY DIAGRAMS AND WORKFLOW SYSTEMS

open access: yesRevista EIA, 2008
Actualmente en los ambientes de desarrollo de software hay un gran interés en buscar y desarrollar técnicas que puedan integrar los sistemas transaccionales con los flujos de trabajo que soportan los procesos del negocio de las organizaciones.
Marta Silvia Tabares   +2 more
doaj  

Causal analysis procedure focused on small software development organizations

open access: yesRevista Facultad de Ingeniería, 2017
Very Small Entities (VSE) dedicated to software development lack of enough resources to adopt causal analysis practices, defined in models as CMMI, due to their complexity and costs.
Kelly Yohanna Zúñiga-Silva   +2 more
doaj   +1 more source

The software development process of ecommerce systems [PDF]

open access: yes
Today, in the new economy, while the possibilities for software are seemingly limitless, so is the growing demand. The problem is that speed and quality have typically been opposing forces in software development, and they still are.
Lazarica, Marinela, Surcel, Traian
core   +1 more source

Organising the knowledge space for software components [PDF]

open access: yes, 2005
Software development has become a distributed, collaborative process based on the assembly of off-the-shelf and purpose-built components. The selection of software components from component repositories and the development of components for these ...
Pahl, Claus
core  

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

A Requirements Engineering Process Adapted to Global Software Development

open access: yesCLEI Electronic Journal, 2016
Global software development is spreading increasingly within companies. Although it provides some competitive advantages, such as speeding up the software delivery, reducing cost, and taking advantage of more economic resources, this working model is a ...
Juan Pablo Mighetti   +1 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Emotional Awareness During Bug Fixes – A Pilot Study [PDF]

open access: yes, 2020
This study examines the effects of a programmer\u27s emotional awareness on progress while fixing bugs. The goal of the study is to capitalize on emotional awareness to ultimately increase progress made during software development.
Loro, Jada O.   +3 more
core   +1 more source

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