Results 71 to 80 of about 8,689,791 (372)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Software-Engineering Process Simulation (SEPS) model [PDF]

open access: yes, 1992
The Software Engineering Process Simulation (SEPS) model is described which was developed at JPL. SEPS is a dynamic simulation model of the software project development process.
Abdel-Hamid, T.   +2 more
core   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Measuring the Pro-Activity of Software Agents [PDF]

open access: yes, 2010
Despite having well-defined characteristics, software agents do not have a developed set of measures defining their quality. Attempts at evaluating software agent quality have focused on some agent aspects, like the development process, whereas others ...
Alonso Amo, Fernando   +2 more
core   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Why emerging leaders should focus on being good postdoctoral supervisors

open access: yesFEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski   +5 more
wiley   +1 more source

The Unified Approach For Organizational Network Vulnerability Assessment

open access: yes, 2013
The present business network infrastructure is quickly varying with latest servers, services, connections, and ports added often, at times day by day, and with a uncontrollably inflow of laptops, storage media and wireless networks.
Jagli, Mrs. Dhanamma   +1 more
core   +1 more source

Development of Multi Platform Geographic Information System Assessment of Prospective Bidikmisi Students Using Reuse Driven Software Development Process Method [PDF]

open access: hybrid, 2022
Muhammad Aris Ganiardi   +6 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Using system dynamics to teach about dependencies, correlation and systemic thinking on the software process workflows

open access: yesIET Software, 2021
It is important to count on tools to help software professionals to evaluate the software process and how it may be affected by factors related to its deployment.
German‐Lenin Dugarte‐Peña   +4 more
doaj   +1 more source

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