Results 61 to 70 of about 83,073 (313)

Software Cost and Effort Estimation: Current Approaches and Future Trends

open access: yesIEEE Access, 2023
Software cost and effort estimation is one of the most significant tasks in the area of software engineering. Research conducted in this field has been evolving with new techniques that necessitate periodic comparative analyses.
Chaudhary Hamza Rashid   +6 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Software Estimation in the Design Stage with Statistical Models and Machine Learning: An Empirical Study

open access: yesMathematics
Accurate estimation of software effort and time in the software development process is a key activity to achieve the necessary product quality. However, underestimation or overestimation of effort has become a key challenge for software development.
Ángel J. Sánchez-García   +3 more
doaj   +1 more source

A soft computing framework for software effort estimation

open access: yesSoft Computing, 2005
Accurate software estimation such as cost estimation, quality estimation and risk analysis is a major issue in software project management. In this paper, we present a soft computing framework to tackle this challenging problem. We first use a preprocessing neuro-fuzzy inference system to handle the dependencies among contributing factors and decouple ...
Huang, Xishi   +3 more
openaire   +4 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

An estimate of necessary effort in the development of software projects [PDF]

open access: yes, 2004
International Workshop on Intelligent Technologies for Software Engineering (WITSE'04). 19th IEEE International Conference on Automated Software Engineering (Linz, Austria, September 20th - 25th, 2004)The estimated of the effort in the development of ...
Rodríguez, Martín   +5 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Categorical Variable Segmentation Model for Software Development Effort Estimation

open access: yesIEEE Access, 2019
This paper proposes a new software development effort estimation model. The new model's design is based on the function point analysis, categorical variable segmentation (CVS), and stepwise regression.
Petr Silhavy   +2 more
doaj   +1 more source

State of the practice in software effort estimation: A survey and literature review

open access: yes, 2022
S.232-245Effort estimation is a key factor for software project success, defined as delivering software of agreed quality and functionality within schedule and budget.
Trendowicz, A., Münch, J., Jeffery, R.
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy