Results 111 to 120 of about 829,080 (295)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Infrastructural justice for responsible software engineering,

Journal of Responsible Technology
In recent years, we have seen many examples of software products unintentionally causing demonstrable harm. Many guidelines for ethical and responsible computing have been developed in response. Dominant approaches typically attribute liability and blame
Sarah Robinson, Jim Buckley, Luigina Ciolfi, Conor Linehan, Clare McInerney, Bashar Nuseibeh, John Twomey, Irum Rauf, John McCarthy   +8 more
doaj   +1 more source

How to form a software engineering capstone team? [PDF]

Heliyon, 2021
Shaikh MK.
europepmc   +1 more source

Software engineering [PDF]

, 1984
Tom Gilb
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The Significance of Software Engineering to Forecast the Public Health Issues: A Case of Saudi Arabia. [PDF]

Front Public Health, 2022
Al-Ahmadi HH.
europepmc   +1 more source

Integrating software engineering into an intermediate programming class [PDF]

, 1988
Laurie Honour Werth
openalex   +1 more source

Falsificationism and Software Engineering

Annals of the Japan Association for Philosophy of Science, 1999
Summary: While Popper's falsificationism has normally been dealt with in the context of such philosophical problems as the rationality of science, I shall consider it here in a practical context, with the help of a model case from software engineering.
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

SEOSS-Queries - a software engineering dataset for text-to-SQL and question answering tasks. [PDF]

Data Brief, 2022
Tomova MT, Hofmann M, Mäder P.
europepmc   +1 more source