Results 51 to 60 of about 881,717 (298)

Unifying Requirements and Code: an Example

open access: yes, 2016
Requirements and code, in conventional software engineering wisdom, belong to entirely different worlds. Is it possible to unify these two worlds? A unified framework could help make software easier to change and reuse. To explore the feasibility of such
B Meyer   +5 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Evaluation of the Likelihood of Friend Request Acceptance in Online Social Networks

open access: yesIEEE Access, 2019
Recent years online social networks (OSNs) have become an essential digital platform in the daily life of billions of earth inhabitants. Despite the advantages of easy communication and information sharing, OSNs users often fell in trouble causing by ...
Vitaliy Mezhuyev   +4 more
doaj   +1 more source

Strategic directions in software engineering and programming languages [PDF]

open access: yesACM Computing Surveys, 1996
The computer revolution is based on the ability of a general-purpose machine to carry out a specific task under the control of special-purpose software. While the wide applicability of stock hardware has driven demand up and manufacturing cost per unit dramatically down, the same trends have led to increasing demand for ever more complex software for ...
Carl A. Gunter   +2 more
openaire   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Issues in Chinese Requirements Specifications: Insights from Survey Data and Static Analysis

open access: yesJOIV: International Journal on Informatics Visualization
Requirements engineering is crucial for software project success. Issues like requirements ambiguity, inconsistency, and unverifiability contribute to unclear, conflicting, or untestable specifications, which can undermine the effectiveness and success ...
He Jiaying   +3 more
doaj   +1 more source

Lightweight Multilingual Software Analysis

open access: yes, 2017
Developer preferences, language capabilities and the persistence of older languages contribute to the trend that large software codebases are often multilingual, that is, written in more than one computer language.
Baird, David   +2 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Toward Reverse Engineering of VBA Based Excel Spreadsheet Applications [PDF]

open access: yes, 2015
Modern spreadsheet systems can be used to implement complex spreadsheet applications including data sheets, customized user forms and executable procedures written in a scripting language.
Amalfitano, Domenico   +4 more
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

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