Results 101 to 110 of about 1,870,230 (325)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

AgentReport: A Multi-Agent LLM Approach for Automated and Reproducible Bug Report Generation

Applied Sciences
Bug reports in open-source projects are often incomplete or low in quality, which reduces maintenance efficiency. To address this issue, we propose AgentReport, a multi-agent pipeline based on large language models (LLMs).
Seojin Choi, Geunseok Yang
doaj   +1 more source

Working Notes from the 1992 AAAI Workshop on Automating Software Design. Theme: Domain Specific Software Design [PDF]

The goal of this workshop is to identify different architectural approaches to building domain-specific software design systems and to explore issues unique to domain-specific (vs. general-purpose) software design. Some general issues that cut across the
Barstow, David, Keller, Richard M., Lowry, Michael R., Tong, Christopher H.   +3 more
core   +1 more source

Group Maintenance Behaviors in the Decision-Making Styles of Self-Organizing Distributed Teams [PDF]

, 2009
Businesses, universities, and other organizations are increasingly reliant on self-organizing, distributed teams which are enabled by information and communication technologies (ICTs).
Crowston, Kevin, Heckman, Robert, Li, Qing, Scialdone, Michael John   +3 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Sustaining CyberWater-VisTrails: A Case Study in Software Upgrades and Reengineering

Information
This study focuses on the process of updating and upgrading a large-scale legacy software system to ensure its compatibility with modern computing environments.
Drew Bieger, Ahmed Sheba, Adham M. Hassan, Sherif Aly, Ranran Chen, Xu Liang, Yao Liang   +6 more
doaj   +1 more source

Deep Neural Network-Based Severity Prediction of Bug Reports

IEEE Access, 2019
Software maintenance is an essential phase of software development. Developers employ issue tracking systems to collect bugs for software improvement. Users submit bugs through such issue tracking systems and decide the severity of reported bugs.
Waheed Yousuf Ramay, Qasim Umer, Xu Cheng Yin, Chao Zhu, Inam Illahi   +4 more
doaj   +1 more source

Improving a data-acquisition software system with abstract data type components [PDF]

data types and object-oriented design are active research areas in computer science and software engineering. Much of the interest is aimed at new software development.
Howard, S. D.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

General Software Platform and Content Description Format for Assembly and Maintenance Task Based on Augmented Reality [PDF]

, 2023
Yiming Shen, Shuntaro Ueda, Yuichiro Fujimoto, Taishi Sawabe, Masayuki Kanbara, Hirokazu Kato   +5 more
openalex   +1 more source