Results 201 to 210 of about 67,834 (260)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Micro Patterns in Agile Software
, 2013 In this paper we present a study on micro patterns in different releases of two software systems developed with Object Oriented technologies and Agile process. Micro patterns are design decisions in code that can be easily automatically recognised. Gil and Maman introduced the concept to support providing objective assessment of design decisions [1 ...
Giulio Concas +4 more
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Software Design Patterns for Information Visualization
IEEE Transactions on Visualization and Computer Graphics, 2006Despite a diversity of software architectures supporting information visualization, it is often difficult to identify, evaluate, and re-apply the design solutions implemented within such frameworks. One popular and effective approach for addressing such difficulties is to capture successful solutions in design patterns, abstract descriptions of ...
Jeffrey Heer, Maneesh Agrawala
exaly +3 more sources
Visual identification of software evolution patterns
Ninth international workshop on Principles of software evolution: in conjunction with the 6th ESEC/FSE joint meeting, 2007 Software evolution plays a key role in the overall lifecycle of a software system. In this phase, software developers extend the capabilities and functionality of the system to meet new user requirements. However, the maintenance process could rapidly lead to phenomena of "source code deterioration".
Jermakovics A, Scotto M, Succi G
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Patterns in scientific software: an introduction
Computing in Science and Engineering, 2002Patterns are well understood methodology for object-oriented software architecture, especially for business applications. Scientific programmers have generally avoided object-oriented approaches because of their heavy computational overhead, but the benefits of using patterns for scientific problems can outweigh their costs. This article introduces the
exaly +2 more sources
Using use case patterns to estimate reusability in software systems
Information and Software Technology, 2006 The applicability of using use case patterns as a basis for software cost estimation in the early stages of software development is described. This required the construction of a use case patterns catalogue using a novel process.
Mohammed Odeh
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Software Patterns in ITS Architectures
International Journal of Artificial Intelligence in Education, 2005The paper discusses ITS architectures in terms of patterns that exist within them. The concept of patterns has received surprisingly little attention so far from researchers in the field of ITS. A recent analysis of a number of existing ITS architectures has revealed that many ITS designers and developers use their own solutions when faced with design ...
Devedžić, Vladan, Harrer, A.
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IEEE Software, 2003
Patterns provide a mechanism for rendering design advice in a reference format. Software design is a massive topic, and when faced with a design problem, one must be able to focus on something as close to the problem as you can get. Patterns can help by trying to identify common solutions to recurring problems.
openaire +1 more source
Patterns provide a mechanism for rendering design advice in a reference format. Software design is a massive topic, and when faced with a design problem, one must be able to focus on something as close to the problem as you can get. Patterns can help by trying to identify common solutions to recurring problems.
openaire +1 more source