Results 211 to 220 of about 7,115,919 (304)

ProteinNetworkSight: a user-friendly platform for transforming co-expression patterns into actionable therapeutic insights through interactive network visualization. [PDF]

Nucleic Acids Res
Nahor O, Migdal N, Gibli A, Tsvitman T, Eldad A, Raveh S, Polinovski G, Zaid D, Kravchenko-Balasha N, Cohen NE.   +9 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Practical crystallography with a transmission electron microscope. [PDF]

J Microsc
Weare BL, Fung KLY, Cardillo-Zallo I, Cull WJ, Fay MW, Argent SP, Brown PD.   +6 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Few-shot neuromorphic vision in a nonlinear photonic network laser. [PDF]

Sci Adv
Ng WK, Dranczewski J, Fischer A, Raziman TV, Saxena D, Farchy T, Stenning K, Peters J, Schmid H, Branford WR, Barahona M, Moselund K, Sapienza R, Gartside JC.   +13 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Body Composition and Thermographic Asymmetry in Older Adults: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Núñez-Rodríguez S, Ortega-Santamaría M, Menéndez-Vega F, Collazo-Riobó C, Alvarez-Pardo S, Berardi A, González-Santos J.   +6 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Comprehensive identification of <i>NLP</i> gene family in <i>Panax ginseng</i>:<i>PgNLP02-01</i> and <i>PgNLP07</i> genes expression analysis in ginseng adventitious roots under MeJA response. [PDF]

Front Plant Sci
Wang A, Hu X, Fan M, Zhao M, Wang Y, Wang K, Zhang M.   +6 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source