Results 61 to 70 of about 2,162,371 (314)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Software improvement process

open access: yes, 2008
Estágio realizado no CERN CO ...
openaire   +2 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Success Factors for Conducting Software-Process Improvement in Web-Based Software Projects

open access: yesCybernetics and Information Technologies
Continuous Software Process Improvement (SPI) is essential for achieving and maintaining high-quality software products. Web-based software enterprises, comprising a substantial proportion of global businesses and forming a cornerstone of the world’s ...
Al-Rousan Thamer
doaj   +1 more source

New Advances in the Machining of Hard Metals using Physics-Based Modeling

open access: yesEngineering Transactions, 2014
The machining of hard metals historically has been understood to be challenging and costly due to its material properties (such as titanium’s low thermal conductivity and high hardness, and nickel’s rapid work-hardening and high strength at elevated ...
Troy D. MARUSICH   +4 more
doaj   +1 more source

Using the ISO/IEC 9126 product quality model to classify defects : a Controlled Experiment [PDF]

open access: yes, 2012
Background: Existing software defect classification schemes support multiple tasks, such as root cause analysis and process improvement guidance. However, existing schemes do not assist in assigning defects to a broad range of high level software goals ...
Carolyn Seaman   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

An approach to reconcile the agile and CMMI contexts in product line development [PDF]

open access: yes, 2006
Software product line approaches produce reusable platforms and architectures for products set developed by specific companies. These approaches are strategic in nature requiring coordination, discipline, commonality and communication.
Botella López, Pere   +2 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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