Results 71 to 80 of about 2,162,371 (314)

Organizational Change Perspectives on Software Process Improvement [PDF]

open access: yes
Many software organizations have engaged in Software Process Improvement (SPI) and experienced the challenges related to managing such complex organizational change efforts.
Balshøj, Hans Henrik   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Relevant Organizational Values in the Implementation of Software Process Improvement Initiatives

open access: yesCLEI Electronic Journal, 2013
In a globalized world, organizational culture plays an important role in companies since it represents one of the main factors of business success in competitive scenarios.
Odette Mestrinho Passos   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Balanced Objective-Quantifiers Method (BOQM) For Software Intensive Organizations Strategies [PDF]

open access: yes, 2008
Spanish university facilitates a method to link the strategic management with Software and Process improvement based on measurement. The method uses the process philosophy to build measurable information in Indicators templates (Based on ISO/IEC 15939 ...
De-Amescua Seco, Antonio
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The third version of the AMBER data reduction software

open access: yes, 2010
We present the third release of the AMBER data reduction software by the JMMC. This software is based on core algorithms optimized after several years of operation.
Altariba, Evelyne   +9 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Software process improvement: Awareness, use, and benefits in Canadian software development firms

open access: yesRAE: Revista de Administração de Empresas, 2017
Since 1982, the software development community has been concerned with the delivery of quality systems. Software process improvement (SPI) is an initiative to avoid the delivery of low quality systems.
Delroy Chevers
doaj  

Tuning COCOMO-II for Software Process Improvement: A Tool Based Approach [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2016
In order to compete in the international software development market the software organizations have to adopt internationally accepted software practices i.e.
SYEDA UMEMA HANI   +2 more
doaj  

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