Results 91 to 100 of about 58,774 (210)

Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial

open access: yesAddiction, EarlyView.
Abstract Background and aims Individuals who engage in illicit or nonmedical opioid use may have elevated risk of health and social consequences, including progression to opioid use disorder (OUD). Preventive interventions to reduce this risk are lacking. This trial tested the impact of a primary care‐integrated collaborative care approach for reducing
Jennifer McNeely   +23 more
wiley   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

open access: yesAndrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Targeting the NR3C1‐ACSL4 Axis Triggers Ferroptosis to Overcome Radioresistance in Prostate Cancer

open access: yesCancer Science, EarlyView.
The glucocorticoid receptor NR3C1 drives prostate cancer radioresistance by upregulating ACSL4. High ACSL4 levels create a lipid metabolic vulnerability. The clinical agent DHA synergizes with ACSL4 to induce lipid peroxidation and ferroptosis, effectively overcoming radioresistance.
Jing Yang   +7 more
wiley   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

open access: yesInsect Molecular Biology, EarlyView.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour   +8 more
wiley   +1 more source

When biology meets materials science – Interdisciplinary applications of electron microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract Research at the interface between biology and materials science creates challenges for electron microscopists. Everything from the sample preparation to the choice of imaging and analytical techniques and the interpretation of the resulting data refuses to sit comfortably within the domain of one discipline or the other.
Martin Saunders   +5 more
wiley   +1 more source

UC2‐ESP: A general‐purpose framework for open‐source microscopy control

open access: yesJournal of Microscopy, EarlyView.
Abstract Building the optical setup for investigating biological questions comes with challenges. A major such challenge is setting up and synchronizing the control of multiple hardware components such as stages, cameras and lasers. With UC2‐ESP, we present a low‐cost electronics system powered by the ESP32 microcontroller (∼$10), designed as an ...
Benedict Diederich   +5 more
wiley   +1 more source

Chronotype in relation to shift work: A cohort study among 37,731 female nurses

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Chronotype may affect tolerance for circadian disruption induced by shift work. This study examines the association between chronotype, self‐reported sleep timing, shift type preference, and sleep problems among nurses, and studies chronotype stability over time.
Linske de Bruijn   +6 more
wiley   +1 more source

Whole‐Night Gentle Rocking Improves Sleep in Poor Sleepers With Insomnia Complaints

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Specific brain oscillations can be manipulated during sleep to improve sleep quality and memory performance. We previously demonstrated that continuous rocking stimulation (0.25 Hz, lateral movement) applied to good sleepers during sleep enhanced stable deep sleep, boosted NREM oscillations (spindles and slow waves) and memory consolidation ...
Aurore A. Perrault   +4 more
wiley   +1 more source

Landscape conservation forecasting to evaluate ecological condition and wildlife habitat suitability in eastern Nevada U.S.A.

open access: yesRestoration Ecology, EarlyView.
Abstract Introduction Cooperation among managers of protected areas and federal multiple use lands with private inholdings to increase restoration success and economies of scale creates ecological and regulatory complexity best studied with state‐and‐transition simulation models (STSM).
Louis Provencher   +7 more
wiley   +1 more source

Regulating via Conditionality: The Instruments of the New Industrial Policy

open access: yesRegulation &Governance, EarlyView.
ABSTRACT Conditionality was a central concern in the development literature of the 1990s. With the significant expansion of targeted public support to private firms since the Great Financial Crisis, the issue of conditionality has once again become a focal point in industrial policy debates.
Fabio Bulfone, Timur Ergen, Erez Maggor
wiley   +1 more source

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