Results 71 to 80 of about 3,923,394 (245)

The Scalability-Efficiency/Maintainability-Portability Trade-off in Simulation Software Engineering: Examples and a Preliminary Systematic Literature Review

, 2016
Large-scale simulations play a central role in science and the industry. Several challenges occur when building simulation software, because simulations require complex software developed in a dynamic construction process. That is why simulation software
Graziotin, Daniel, Lindner, Florian, Mehl, Miriam, Pfander, David, Pflüger, Dirk, Valentin, Julian, Wagner, Stefan, Wang, Yang   +7 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Using entropy measures for comparison of software traces

, 2012
The analysis of execution paths (also known as software traces) collected from a given software product can help in a number of areas including software testing, software maintenance and program comprehension.
Davison, M., Miranskyy, A. V., Murtaza, S. S., Reesor, M.   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Complementary Local–Global Optimization for Few-Shot Object Detection in Remote Sensing

Remote Sensing
Few-shot object detection (FSOD) in remote sensing remains challenging due to the scarcity of annotated samples and the complex background environments in aerial images.
Yutong Zhang, Xin Lyu, Xin Li, Siqi Zhou, Yiwei Fang, Chenlong Ding, Shengkai Gao, Jiale Chen   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Boosting the Transferability of Ensemble Adversarial Attack via Stochastic Average Variance Descent

IET Information Security
Adversarial examples have the property of transferring across models, which has created a great threat for deep learning models. To reveal the shortcomings in the existing deep learning models, the method of the ensemble has been introduced to the ...
Lei Zhao, Zhizhi Liu, Sixing Wu, Wei Chen, Liwen Wu, Bin Pu, Shaowen Yao   +6 more
doaj   +1 more source

Accounting for the Uncertainty in the Evaluation of Percentile Ranks

, 2012
In a recent paper entitled "Inconsistencies of Recently Proposed Citation Impact Indicators and how to Avoid Them," Schreiber (2012, at arXiv:1202.3861) proposed (i) a method to assess tied ranks consistently and (ii) fractional attribution to percentile
Leydesdorff, Loet
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Multi-Stage Frequency Attention Network for Progressive Optical Remote Sensing Cloud Removal

Remote Sensing
Cloud contamination significantly impairs optical remote sensing images (RSIs), reducing their utility for Earth observation. The traditional cloud removal techniques, often reliant on deep learning, generally aim for holistic image reconstruction, which
Caifeng Wu, Feng Xu, Xin Li, Xinyuan Wang, Zhennan Xu, Yiwei Fang, Xin Lyu   +6 more
doaj   +1 more source