Results 51 to 60 of about 32,056,537 (304)

A review of optimization methods for computation offloading in edge computing networks

Digital Communications and Networks, 2023
Handling the massive amount of data generated by Smart Mobile Devices (SMDs) is a challenging computational problem. Edge Computing is an emerging computation paradigm that is employed to conquer this problem. It can bring computation power closer to the
Kuanishbay Sadatdiynov, Laizhong Cui, Lei Zhang, Joshua Zhexue Huang, Salman Salloum, Mohammad Sultan Mahmud   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Analyzing the 2021 Kaseya Ransomware Attack: Combined Spearphishing Through SonicWall SSLVPN Vulnerability

IET Information Security
In July 2021, the IT management software company Kaseya was the victim of a ransomware cyberattack. The perpetrator of this attack was ransomware evil (REvil), an allegedly Russian-based ransomware threat group. This paper addresses the general events of
Suman Bhunia, Matthew Blackert, Henry Deal, Andrew DePero, Amar Patra   +4 more
doaj   +1 more source

Automatic Sugarcane Disease Detection and Outbreak Alert System using Deep Learning

JISR on Computing
Agriculture Agriculture is a vital sector in Pakistan, with sugarcane being the second-largest crop. However, the industry faces challenges due to crop diseases, prompting the need for innovative solutions.
Munaf Rashid, Zuha Khan, Saeed Usmani, Asadullah Maliyawala, Kashif Iqbal   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The T experiments: errors in scientific software [PDF]

, 1997
Extensive tests showed that many software codes widely used in science and engineering are not as accurate as we would like to think. It is argued that better software engineering practices would help solve this problem, but realizing that the problem ...
Hatton, Leslie, L. Hatton
core   +2 more sources

MATADOR: a magic matrix-based framework for tamper detection and image recovery

Journal of King Saud University: Computer and Information Sciences
Ensuring the integrity and authenticity of digital medical images is crucial for healthcare security and digital forensics, as image tampering can have serious consequences.
Thilina Mendis, Farah Kandah, Lalith Medury   +2 more
doaj   +1 more source

Dynamic Multiobjective Optimization with Multiple Response Strategies Based on Linear Environment Detection

Complexity, 2020
Dynamic multiobjective optimization problems (DMOPs) bring more challenges for multiobjective evolutionary algorithm (MOEA) due to its time-varying characteristic.
Qiyuan Yu, Shen Zhong, Zun Liu, Qiuzhen Lin, Peizhi Huang   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source