Results 311 to 320 of about 1,127,606 (325)
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Endeavour, 1965
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Solid-Phase Synthesis of Fullerene-peptides
Journal of the American Chemical Society, 2002The solid-phase synthesis of peptides (SPPS) containing [60]fullerene-functionalized amino acids is reported. A new amino acid, fulleropyrrolidino-glutamic acid (Fgu), is used for the SPPS of a series of analogues of different length based on the natural Leu(5)-Enkephalin and on cationic antimicrobial peptides.
PANTAROTTO, DAVIDE +7 more
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Recent advances in solid-phase synthesis [PDF]
ChemInform, 1997 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Solid‐phase peptide synthesis on proteins
International Journal of Peptide and Protein Research, 1993A new method for solid‐phase peptide synthesis in which a protein is used as the solid support has been developed. Two aspects of the method have been demonstrated. The peptides H‐Phe‐Leu‐Glu‐Glu‐Val‐OH (1) and H‐Leu‐Leu‐Ala‐Glj‐Val‐OH (2), respectively, were synthesized on the amino groups of BSA via a cleaveable linker, using the Fmoc group ...
Hansen, Paul Robert +2 more
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Fmoc Solid-Phase Peptide Synthesis
2015Synthetic peptides are important as drugs and in research. Currently, the method of choice for producing these compounds is solid-phase peptide synthesis. In this nonspecialist review, we describe the scope and limitations of Fmoc solid-phase peptide synthesis. Furthermore, we provide a detailed protocol for Fmoc peptide synthesis.
Hansen, Paul Robert, Oddo, Alberto
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Need for Solid-Phase Thinking in Solid-Phase Synthesis
1973The invention of the solid-phase method looked like an ingenious trick to overcome some of the unpleasant features of the classical methods. As we know today, the ingenuity of the trick remains, but only a large investment of heavy real effort will eventually, if ever, work it into a real progress over the classical approach.
P. Fankhauser, M. Brenner
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[48] Solid-phase peptide synthesis
1977Publisher Summary In solid-phase peptide synthesis, protein is synthesized by the successive addition of appropriately protected amino acid residues to a completely insoluble growing point. The majority of peptides prepared by solid-phase techniques have been synthesized in a stepwise fashion with progression from the COOH-terminal to the NH 2 ...
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Solid-Phase Synthesis of Octapeptin Lipopeptides
2019Octapeptins are naturally derived cyclic lipopeptide antibiotics with activity against a range of Gram-negative pathogens, including highly resistant strains. Octapeptin C4, an exemplar of the class, was synthesized using a combination of Fmoc solid-phase peptide synthesis (SPPS) and solution-phase cyclization.
Hansford, Karl A. +3 more
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1991
This chapter discusses solid phase peptide synthesis, an idea which first appeared in a scientific publication by Merrifield in 1963. It explains why the term ‘solid phaseȉ is misleading, elaborating that the reactions do not take place in or on the surfaces of solid phases, but in gel systems produced by the penetration of solvent and solute molecules
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This chapter discusses solid phase peptide synthesis, an idea which first appeared in a scientific publication by Merrifield in 1963. It explains why the term ‘solid phaseȉ is misleading, elaborating that the reactions do not take place in or on the surfaces of solid phases, but in gel systems produced by the penetration of solvent and solute molecules
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1988
By the conventional methods of organic synthesis, preparation of peptides containing more than just a few amino acids is an arduous task. Introduction of blocking groups, coupling reactions and deprotection steps entail a large number of operations, such as washing the reaction mixtures neutral after coupling, precipitation or crystallization of ...
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By the conventional methods of organic synthesis, preparation of peptides containing more than just a few amino acids is an arduous task. Introduction of blocking groups, coupling reactions and deprotection steps entail a large number of operations, such as washing the reaction mixtures neutral after coupling, precipitation or crystallization of ...
openaire +2 more sources