Results 71 to 80 of about 1,773,765 (367)

Synthesis of high-oxidation Y-Ba-Cu-O phases in superoxygenated thin films

, 2018
It is known that solid-state reaction in high-pressure oxygen can stabilize high-oxidation phases of Y-Ba-Cu-O superconductors in powder form. We extend this superoxygenation concept of synthesis to thin films which, due to their large surface-to-volume ...
Botton, G. A., Gauquelin, N., Hawthorn, D. G., McMahon, C., Wei, J. Y. T., Zhang, H.   +5 more
core   +1 more source

Novel sulfur and selenium containing bis-α-amino acids from 4-hydroxyproline [PDF]

, 2010
The synthesis of new substituted prolines carrying at C-4 a second α-amino acid residue is reported. The amino acid, l-cysteine or l-selenocysteine, is linked to the proline ring through the sulfur or the selenium atom, respectively.
CAPUTO, ROMUALDO, D. MASTROIANNI, DELLA GRECA, MARINA, I. de PAOLA, LONGOBARDO, LUIGI   +4 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Evolution of superconductivity in LaO1-xFxBiS2 prepared by high pressure technique

, 2012
Novel BiS2-based superconductors LaO1-xFxBiS2 prepared by the high pressure synthesis technique were systematically studied. It was found that the high pressure annealing strongly the lattice as compared to the LaO1-xFxBiS2 samples prepared by ...
Deguchi, K., Demura, S., Denholme, S. J., Fujioka, M., Hara, H., Miura, O., Mizuguchi, Y., Okazaki, H., Ozaki, T., Takano, Y., Takeya, H., Watanabe, T., Yamaguchi, T.   +12 more
core   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

SASRIN™ a Versatile Tool in Peptide Synthesis and Solid-Phase Organic Chemistry

CHIMIA, 1999
The synthesis of the 4-(3-methoxy-4-(hydroxymethyl)phenoxymethyl) derivative of polystyrene-co-divinylbenzene (SASRIN™), its derivatives and its application in solid-phase peptide synthesis will be briefly reviewed in this paper.
Monika Mergler, Jacques Gosteli, Peter Grogg, Rolf Nyfeler, Rudolf Tanner   +4 more
doaj  

Fast Method for Synthesis of Alkyl and Aryl-N-Methylnitrones

Molecules, 2011
A simple, fast, efficient and eco-friendly procedure was developed for the synthesis of alkyl and aryl-N-methylnitrones. The corresponding nitrones of aromatic aldehydes, aliphatic aldehydes and alicyclic carbonyl compounds were prepared from N ...
Yilmaz Yildirir, Naki Colak, Hamdi Ozkan, Serkan Yavuz   +3 more
doaj   +1 more source

Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer [PDF]

, 2016
The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules, have mainly been explored in free solution.We report on the design, synthesis, and conformational behavior of photoresponsive foldamers bound in a phospholipid ...
Clayden, Jonathan, De Poli, Matteo, Lorch, Mark, Quinonero, Ophélie, Webb, Simon J., Zawodny, Wojciech   +5 more
core   +2 more sources

Green Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under Green Conditions

, 2016
N,N-Dimethylformamide (DMF), N-methyl-2-pyrrolidone, and dichloromethane (DCM) are the most widely used solvents for Fmoc solid-phase peptide synthesis (SPPS).
Yahya E. Jad, G. Acosta, T. Govender, H. Kruger, A. El‐Faham, B. G. Torre, F. Albericio   +6 more
semanticscholar   +1 more source

Automated solid-phase synthesis of oligosaccharides containing sialic acids

Beilstein Journal of Organic Chemistry, 2015
A sialic acid glycosyl phosphate building block was designed and synthesized. This building block was used to prepare α-sialylated oligosaccharides by automated solid-phase synthesis selectively.
Chian-Hui Lai, H. S. Hahm, Chien‐Fu Liang, P. Seeberger   +3 more
semanticscholar   +1 more source