Results 71 to 80 of about 12,547 (240)
The solid-phase peptide synthesis (SPPS) strategy, as the main procedure of peptide manufacturing, has a profound impact on the research of peptides.
D. Luo+8 more
doaj
Versatile Monitoring Tools in Parallel Solid-Phase Synthesis
Parallel synthesis on solid-phase is routinely applied in our combinatorial chemistry efforts for lead finding and lead optimization in drug discovery.
Eduard R. Felder+3 more
doaj +1 more source
The successful in situ polymerization of microtubules in giant polymer‐lipid hybrid vesicles is illustrated. The microtubules formed in the giant hybrid vesicles exhibit different morphologies including lumenal network formation and membrane association. Abstract Creating artificial cells with a dynamic cytoskeleton, akin to those in living cells, is a
Paula De Dios Andres+4 more
wiley +1 more source
The Facile Solid-Phase Synthesis of Thiazolo-Pyrimidinone Derivatives
A thiazolo-pyrimidinone derivative library was developed through a facile solid-phase synthesis method. For the reaction, the thiazolo[4,5-d]pyrimidin-7(6H)-one structure was synthesized through efficient Thorpe–Ziegler and cyclization reactions.
Shuanghui Hua, Jimin Moon, Taeho Lee
doaj +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Toward Design Principles for Biomolecular Condensates for Metabolic Pathways
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André+3 more
wiley +1 more source
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua+5 more
wiley +1 more source
Solid-phase synthesis of a tetradepsipeptide containing three hydroxy acids [PDF]
L. A. Shchukina+2 more
openalex +1 more source
In this study, exciting new bi‐/multi‐linear elastic behavior of soft elastic composites that accompany the activation of wrinkling in the embedded interfacial layers is analyzed. The new features and performance of these composite materials, including dramatic enhancements in energy storage, can be tailored by the concentration of interfacial layers ...
Narges Kaynia+2 more
wiley +1 more source
Maillard Type Reaction for Electroless Copper Plating onto Ceramic Nanoparticles
This work presents the manufacturing of copper‐plated ceramic nanoparticles in an environmentally friendly way. Supported by organic functionalizations with pectin an electroless plating step can be performed. Sustainable reagents like xylose, and several amino acids are used for the reduction process.
Lukas Mielewczyk+8 more
wiley +1 more source