Results 1 to 10 of about 21,788 (158)

Controllable Shrinking Fabrication of Solid-State Nanopores [PDF]

open access: yesMicromachines, 2022
Nanopores have attracted widespread attention in DNA sequencing and protein or biomarker detection, owning to the single-molecule-scale detection accuracy.
Xin Lei   +4 more
doaj   +6 more sources

Controlling DNA Translocation Through Solid-state Nanopores [PDF]

open access: yesNanoscale Research Letters, 2020
Compared with the status of bio-nanopores, there are still several challenges that need to be overcome before solid-state nanopores can be applied in commercial DNA sequencing. Low spatial and low temporal resolution are the two major challenges.
Zhishan Yuan   +4 more
doaj   +5 more sources

Fabrication and Applications of Solid-State Nanopores [PDF]

open access: yesSensors, 2019
Nanopores fabricated from synthetic materials (solid-state nanopores), platforms for characterizing biological molecules, have been widely studied among researchers.
Qi Chen, Zewen Liu
doaj   +5 more sources

Detecting DNA depurination with solid-state nanopores. [PDF]

open access: yesPLoS ONE, 2014
Among the different types of DNA damage that occur endogenously in the cell, depurination is especially prevalent. These lesions can initiate mutagenesis and have been implicated in a variety of diseases, including cancer.
Michael M Marshall   +3 more
doaj   +5 more sources

Simple Fabrication of Solid-State Nanopores on a Carbon Film [PDF]

open access: yesMicromachines, 2021
Solid-state nanopores are widely used as a platform for stochastic nanopore sensing because they can provide better robustness, controllable pore size, and higher integrability than biological nanopores.
Natsumi Takai   +3 more
doaj   +2 more sources

Nanopore fabrication by controlled dielectric breakdown. [PDF]

open access: yesPLoS ONE, 2014
Nanofabrication techniques for achieving dimensional control at the nanometer scale are generally equipment-intensive and time-consuming. The use of energetic beams of electrons or ions has placed the fabrication of nanopores in thin solid-state ...
Harold Kwok   +2 more
doaj   +5 more sources

Identification of nine mammal monosaccharides by solid-state nanopores [PDF]

open access: yesScientific Reports
Glycans, nucleic acids and proteins are three major classes of natural biopolymers. The extremely high diversity of isomerization makes structural elucidation of glycans the most challenging job among three classes.
Yunze Sun   +7 more
doaj   +2 more sources

Fast Fabrication of Solid-State Nanopores for DNA Molecule Analysis [PDF]

open access: yesNanomaterials, 2021
Solid-state nanopores have been developed as a prominent tool for single molecule analysis in versatile applications. Although controlled dielectric breakdown (CDB) is the most accessible method for a single nanopore fabrication, it is still necessary to
Yin Zhang   +4 more
doaj   +2 more sources

Digital immunoassay for biomarker concentration quantification using solid-state nanopores [PDF]

open access: yesNature Communications, 2021
The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulating ...
Liqun He   +7 more
doaj   +2 more sources

Slowing down DNA translocation through solid-state nanopores by edge-field leakage [PDF]

open access: yesNature Communications, 2021
Solid-state nanopores can serve as single molecule sensors for DNA sequencing, but the current designs suffer from fast DNA translocation so low detectivity. Wang et al.
Ceming Wang   +4 more
doaj   +2 more sources

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