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Solid-state nanopores and nanopore arrays optimized for optical detection

Nanoscale, 2014
Controllable reduction of the local fluorescence around solid-state nanopores and nanopore arrays enables optical recognition of molecular translocations and a route towards massively-parallel detection.
Furat, Sawafta   +4 more
openaire   +2 more sources

Fabrication of solid‐state nanopores and its perspectives

ELECTROPHORESIS, 2015
Nanofluidics is becoming an extensively developing technique in the field of bioanalytical chemistry. Nanoscale hole embed in an insulating membrane is employed in a vast variety of sensing platforms and applications. Although, biological nanopores have several attractive characteristics, in this paper, we focused on the solid‐state nanopores due to ...
Jiri, Kudr   +6 more
openaire   +2 more sources

Solid-state nanopore channels with DNA selectivity

Nature Nanotechnology, 2007
Solid-state nanopores have emerged as possible candidates for next-generation DNA sequencing devices. In such a device, the DNA sequence would be determined by measuring how the forces on the DNA molecules, and also the ion currents through the nanopore, change as the molecules pass through the nanopore.
Iqbal, Samir Muzaffar   +2 more
openaire   +3 more sources

On Induced Surface Charge in Solid-State Nanopores

Langmuir, 2020
Solid-state nanopores constitute a versatile platform for study of ion transport in nanoconfinement. The electrical double layer (EDL) plays a vital role in such nanoconfinements, but effects of induced surface charge on the EDL in the presence of an external transmembrane electric field are yet to be characterized.
Yao Yao   +3 more
openaire   +2 more sources

Solid-state nanopores for biosensing with submolecular resolution

Biochemical Society Transactions, 2012
Biological cell membranes contain various types of ion channels and transmembrane pores in the 1–100 nm range, which are vital for cellular function. Individual channels can be probed electrically, as demonstrated by Neher and Sakmann in 1976 using the patch-clamp technique [Neher and Sakmann (1976) Nature 260, 799–802].
Japrung, Deanpen   +3 more
openaire   +3 more sources

Dynamics of Colloids in Single Solid-State Nanopores

The Journal of Physical Chemistry B, 2011
We use solid-state nanopores to study the dynamics of single electrically charged colloids through nanopores as a function of applied voltage. We show that the presence of a single colloid inside of the pore changes the pore resistance, in agreement with theory.
Bacri, Laurent   +7 more
openaire   +3 more sources

DNA-functionalized solid state nanopore for biosensing

Nanotechnology, 2010
The possible use of nanopores for single DNA molecules biosensing has been demonstrated, but much remains to do in order to develop advanced engineered devices with enhanced stability, and controlled geometry and surface properties. Here we present morphological and electrical characterization of solid state silicon nitride nanopores fabricated by ...
MUSSI, VALENTINA   +7 more
openaire   +4 more sources

Single-Molecule Analysis with Solid-State Nanopores

Annual Review of Analytical Chemistry, 2019
Solid-state nanopores and nanopipettes are an exciting class of single-molecule sensors that has grown enormously over the last two decades. They offer a platform for testing fundamental concepts of stochasticity and transport at the nanoscale, for studying single-molecule biophysics and, increasingly, also for new analytical applications and in ...
openaire   +2 more sources

Solid-State Nanopore-Based Cell Analysis

Analytical Chemistry
Real-time, accurate monitoring of cells and intracellular molecules is crucial for a deeper understanding of biological processes and disease diagnosis. Nanopore sensing technology has been widely applied in the field of cell analysis in recent years due to its advantages of being label-free, real-time response, and simple operation.
Kewen Song   +6 more
openaire   +2 more sources

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