Results 231 to 240 of about 18,268,240 (267)
Solid state nanopores for gene expression profiling
Superlattices and Microstructures, 2009 Abstract Recently, nanopore technology has been introduced for genome analysis. Here we show results related to the possibility of preparing “engineered solid state nanopores”. The nanopores were fabricated on a suspended Si 3 N 4 membrane by Focused Ion Beam (FIB) drilling and chemically functionalized in order to covalently bind oligonucleotides ...
MUSSI, VALENTINA +7 more
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Slowing Down DNA Translocation Through Solid‐State Nanopores by Pressure
Small, 2013 The effect of applied pressure on event duration distributions in 3 kb dsDNA translocation is systematically investigated. The effects of pressure magnitude and nanopore size on the length discrimination between 615 bp and 1.14 kbp dsDNA is studied.
Qing Zhao
exaly +2 more sources
Pressure-Controlled Motion of Single Polymers through Solid-State Nanopores [PDF]
Nano Letters, 2013 Voltage-biased solid-state nanopores are well established in their ability to detect and characterize single polymers, such as DNA, in electrolytes. The addition of a pressure gradient across the nanopore yields a second molecular driving force that ...
Bo Lu, Dapeng Yu, David Hoogerheide
exaly +3 more sources
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Fabrication of solid-state nanopores
Nanotechnology, 2022Abstract Nanopores are valuable single-molecule sensing tools that have been widely applied to the detection of DNA, RNA, proteins, viruses, glycans, etc. The prominent sensing platform is helping to improve our health-related quality of life and accelerate the rapid realization of precision medicine.
Kabin Lin +7 more
openaire +2 more sources
Microfluidic multiplexing of solid-state nanopores
Journal of Physics: Condensed Matter, 2017Abstract Although solid-state nanopores enable electronic analysis of many clinically and biologically relevant molecular structures, there are few existing device architectures that enable high-throughput measurement of solid-state nanopores.
Tarun Jain +4 more
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Nature Reviews Materials, 2020
Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare.
Liang Xue +5 more
openaire +2 more sources
Nanopore-based sensors have established themselves as a prominent tool for solution-based, single-molecule analysis of the key building blocks of life, including nucleic acids, proteins, glycans and a large pool of biomolecules that have an essential role in life and healthcare.
Liang Xue +5 more
openaire +2 more sources
Nature Nanotechnology, 2007
The passage of individual molecules through nanosized pores in membranes is central to many processes in biology. Previously, experiments have been restricted to naturally occurring nanopores, but advances in technology now allow artificial solid-state nanopores to be fabricated in insulating membranes.
openaire +2 more sources
The passage of individual molecules through nanosized pores in membranes is central to many processes in biology. Previously, experiments have been restricted to naturally occurring nanopores, but advances in technology now allow artificial solid-state nanopores to be fabricated in insulating membranes.
openaire +2 more sources
DNA Origami Gatekeepers for Solid‐State Nanopores
Angewandte Chemie, 2012DNA has it covered: DNA origami gatekeeper nanoplates convert nanopores in solid-state membranes into versatile devices for label-free macromolecular sensing applications. The custom apertures in the nanoplates can be chemically addressed for sequence-specific detection of DNA.
Ruoshan Wei +3 more
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Rescalable solid-state nanopores
AIP Conference Proceedings, 2017Nanopores in 10–30 nm thickness Si4N3 membranes were milled using Ga+ ions. Dose dependence of the hole diameter and shape was established and explained as resulting from the intensity distribution of the focused ion beam. The initial diameter of the milled pore is dependent on the full-width half-maximum of the axial portion of the beam, whereas shape
Armandas Balčytis +4 more
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Solid-State Nanopore Technologies for Nanopore-Based DNA Analysis
Nanomedicine, 2007Nanopore-based DNA analysis is a new single-molecule technique that involves monitoring the flow of ions through a narrow pore, and detecting changes in this flow as DNA molecules also pass through the pore. It has the potential to carry out a range of laboratory and medical DNA analyses, orders of magnitude faster than current methods.
Ken, Healy +2 more
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