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Solid-state nanopores and nanopore arrays optimized for optical detection
Nanoscale, 2014Controllable reduction of the local fluorescence around solid-state nanopores and nanopore arrays enables optical recognition of molecular translocations and a route towards massively-parallel detection.
Furat, Sawafta +4 more
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Fabrication of solid‐state nanopores and its perspectives
ELECTROPHORESIS, 2015Nanofluidics is becoming an extensively developing technique in the field of bioanalytical chemistry. Nanoscale hole embed in an insulating membrane is employed in a vast variety of sensing platforms and applications. Although, biological nanopores have several attractive characteristics, in this paper, we focused on the solid‐state nanopores due to ...
Jiri, Kudr +6 more
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Solid-state nanopore channels with DNA selectivity
Nature Nanotechnology, 2007Solid-state nanopores have emerged as possible candidates for next-generation DNA sequencing devices. In such a device, the DNA sequence would be determined by measuring how the forces on the DNA molecules, and also the ion currents through the nanopore, change as the molecules pass through the nanopore.
Iqbal, Samir Muzaffar +2 more
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Selective (Bio)Functionalization of Solid-State Nanopores
ACS Applied Materials & Interfaces, 2015We present a method to selectively (bio)functionalize nanoscale features with the same materials chemistry. It was successfully combined with nanosphere lithography to fabricate and functionalize solid-state nanopores with PEG-brushes, supported lipid membranes, and functional proteins over large areas.
Pla-Roca Mateu +3 more
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Dynamics of Colloids in Single Solid-State Nanopores
The Journal of Physical Chemistry B, 2011We use solid-state nanopores to study the dynamics of single electrically charged colloids through nanopores as a function of applied voltage. We show that the presence of a single colloid inside of the pore changes the pore resistance, in agreement with theory.
Bacri, Laurent +7 more
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On Induced Surface Charge in Solid-State Nanopores
Langmuir, 2020Solid-state nanopores constitute a versatile platform for study of ion transport in nanoconfinement. The electrical double layer (EDL) plays a vital role in such nanoconfinements, but effects of induced surface charge on the EDL in the presence of an external transmembrane electric field are yet to be characterized.
Yao Yao +3 more
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DNA-functionalized solid state nanopore for biosensing
Nanotechnology, 2010The possible use of nanopores for single DNA molecules biosensing has been demonstrated, but much remains to do in order to develop advanced engineered devices with enhanced stability, and controlled geometry and surface properties. Here we present morphological and electrical characterization of solid state silicon nitride nanopores fabricated by ...
MUSSI, VALENTINA +7 more
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Solid-state nanopores for biosensing with submolecular resolution
Biochemical Society Transactions, 2012Biological cell membranes contain various types of ion channels and transmembrane pores in the 1–100 nm range, which are vital for cellular function. Individual channels can be probed electrically, as demonstrated by Neher and Sakmann in 1976 using the patch-clamp technique [Neher and Sakmann (1976) Nature 260, 799–802].
Japrung, Deanpen +3 more
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Solid state nanopores for gene expression profiling
Superlattices and Microstructures, 2009Abstract Recently, nanopore technology has been introduced for genome analysis. Here we show results related to the possibility of preparing “engineered solid state nanopores”. The nanopores were fabricated on a suspended Si 3 N 4 membrane by Focused Ion Beam (FIB) drilling and chemically functionalized in order to covalently bind oligonucleotides ...
MUSSI, VALENTINA +7 more
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Solid-State Nanopores for Biomolecular Analysis and Detection
2023Advances in nanopore technology and data processing have rendered DNA sequencing highly accessible, unlocking a new realm of biotechnological opportunities. Commercially available nanopores for DNA sequencing are of biological origin and have certain disadvantages such as having specific environmental requirements to retain functionality.
Annina, Stuber +3 more
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